Results 231 to 240 of about 2,699,979 (303)

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

When Host's Defenses Take a NAP: Nucleoid-Associated Proteins as Integrators of Infection and Virulence. [PDF]

Microorganisms
Sanogo H, Hoareau M, Crémazy F.
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Systematic Benchmarking of DNA Sequence Encoding Strategies for Predicting Regulatory Effects of Non-Coding SNPs. [PDF]

Int J Mol Sci
Jin H, Bao Y, Li W, Yang C, Wang W, Cai W, Liu Z, Lin GN.   +7 more
europepmc   +1 more source

An Efficient Biological Codon Recognition Reservoir Computing System Based on Low‐Energy Epitaxial Hf0.52Zr0.48O2 Ferroelectric Memristors

Advanced Science, EarlyView.
This work reports on epitaxially grown Hf0.52Zr0.48O2 ferroelectric memristors with high stability (high durability exceeding 108 cycles and a retention time exceeding 104 s for 16 states) and ultra‐low operating energy consumption (∼121 fJ). A memristor array‐based reservoir computing system is constructed and applied for the first time in the field ...
Ying Liu, Jikang Xu, Yongqing Jia, Wenxuan Wang, Weifeng Zhang, Biao Yang, Xiaobing Yan   +6 more
wiley   +1 more source

A Confirmatory, Dual Center Nonhuman Primate Study on the Efficacy of Novel Oropharyngeal Spray Immunization With an Adenoviral Vector Vaccine Against RSV-Important Lessons Learned. [PDF]

J Med Primatol
Tenbusch M, Koopman G, Mooij P, Roshani B, Irrgang P, Lapuente D, Kondova I, Bogers WM, Remarque EJ, Vestweber R, Merida Ruiz SA, Krüger N, Meyer S, Gefeller O, Stahl-Hennig C, Überla K.   +15 more
europepmc   +1 more source

Decoupling Fabrication From Encoding: DNA-Addressable Template Microparticles for Large, User-Defined Optical Barcode Libraries. [PDF]

Adv Sci (Weinh)
Eguchi A, Iwamoto Y, Tokuda H, Narita H, Martin AM, Ota S.   +5 more
europepmc   +1 more source

DNA-DETR: sequence representation matters in object detection for functional genomic elements. [PDF]

Brief Bioinform
Tsai BS, Wong JY, Tsai HK.
europepmc   +1 more source

An expanded realm of anti-CRISPR-associated proteins and regulatory mechanisms. [PDF]

Nucleic Acids Res
Feussner M, Birkholz N, Lee SY, Beisel CL, Park HH, Brown CM, Fineran PC, Weinberg Z.   +7 more
europepmc   +1 more source

Detection of bacterial gene expression elements on Tobacco mosaic virus RNA using cDNA analysis. [PDF]

PLoS One
Nishimiya Y.
europepmc   +1 more source