Results 231 to 240 of about 2,593,032 (311)

Giant transposable elements drive genetic diversification in <i>Aspergillus oryzae</i>, a domesticated fungus traditionally used in food fermentation. [PDF]

iScience
Hamanaka Y, Katayama T, Chiken Y, Nishiguchi K, Yamaguchi K, Shigenobu S, Maruyama JI.   +6 more
europepmc   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source

Polus: a context-aware enhancement framework for DNA storage via transformer-based soft-decision decoding. [PDF]

Bioinformatics
Ding L, Wang K, Zhang H, Xie S, Wang J, Liu B, Wang G, Liu L, Zhu Z.   +8 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Prediction of DNA N4-Methylcytosine Sites Based on a Position-Aligned Multi-branch Fusion Network. [PDF]

Comput Struct Biotechnol J
Wang H, Li J, Ruan Y, Feng H.
europepmc   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Methylation Dynamics in <i>Helicobacter pylori</i>: Exploring Acidic Stress Effects on Epigenetic Acclimation. [PDF]

Microorganisms
Patterson SK, He JY, Xu Y, Greene EM, Poznyak Y, Nye MV, Forsyth MH.   +6 more
europepmc   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

Advanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena, Soyeon Lee, Youngeun Choi, Jonathan L'Heureux‐Hache, Jiaying Liu, Sadman Sakib, Sara M. Imani, Marek Smieja, Yingfu Li, Todd Hoare, Leyla Soleymani   +10 more
wiley   +1 more source

Plasmid-DNA Encoded <i>gata3</i> and <i>eomes</i> Increase Antibody Response and Performance of an Inactivated Salmonid Alphavirus Subtype 3 Vaccine. [PDF]

Pharmaceutics
Figueiredo F, Sørmo KG, Pettersen A, Chi H, Swain JK, Erkinharju T, Swain T, Bhat S, Præbel K, Peruzzi S, Godfroid J, Evensen Ø, Munang'andu HM, Dalmo RA.   +13 more
europepmc   +1 more source