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Rapid protamine evolution suppresses meiotic drive in <i>Drosophila</i>. [PDF]
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DNA Encoding of Natural Products
2022DNA-encoded library (DEL) links the powers of genetics and chemicals via high-efficient enzymatic ligation of DNA barcodes and the "split and pool" combinatorial synthesis. Natural products (NPs) are evolutionary optimized compounds that have played a key role in the history of human drug discovery.
Hongtao, Xu, Peixiang, Ma
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Remarks on Relativisations and DNA Encodings
2003Biomolecular computing requires the use of carefully crafted DNA words. We compare and integrate two known different theoretical approaches ([2,3]) to the encoding problem for DNA languages: one is based on a relativization of concepts related to comma free codes, the other is a generalization to any given mapping θ of the notion of words appearing as ...
FERRETTI, CLAUDIO, MAURI, GIANCARLO
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The Capacity of DNA for Information Encoding
2005Information encoding and processing in DNA has proved to be an important problem for biomolecular computing, including the well studied codeword design problem. A lower bound is established for the capacity of DNA to encode information using a combinatorial model of DNA homology given by the so-called h-distance. This bound decreases exponentially with
Vinhthuy T. Phan, Max H. Garzon
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Digital Information Encoding on DNA
2003Novel approaches to information encoding with DNA are explored using a new Watson-Crick structure for binary strings more appropriate to model DNA hybridization. First, a Gibbs energy analysis of codeword sets is obtained by using a template and extant error-correcting codes.
Max H. Garzon +2 more
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Codes, Involutions, and DNA Encodings
2002DNA computing as a field started in 1994 when Leonard Adleman solved a hard computational problem entirely by manipulations of DNA molecules in a test tube [1]. The premise behind DNA computing is that DNA is capable of storing information, while various laboratory techniques that operate on and modify DNA strands (called bio-operations in the sequel ...
Lila Kari, Rob Kitto, Gabriel Thierrin
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Mitochondrial DNA-encoded defects
Mitochondrial DNA (mtDNA)-related mitochondrial diseases are clinically heterogeneous, can occur at any age, and can manifest with a wide range of clinical symptoms. The complexity of mitochondrial disease necessitates clinical care and genetic and functional diagnostics at a dedicated center with the requisite expertise and intercollegial exchange.Wagner, M., Wortmann, S.B.
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