Results 31 to 40 of about 2,699,979 (303)

Local alignment of generalized k-base encoded DNA sequence

open access: yesBMC Bioinformatics, 2010
Background DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however observe an encoded form of the sequence, rather than each DNA base ...
Nelson Stanley F   +2 more
doaj   +1 more source

DNA-Compatible Diversification of Indole Activated Alcohols via a Direct Dehydrative Coupling Strategy

open access: yes, 2022
Indole-based diversification is highly desired in the DNA-encoded chemical library construction. Herein, we present a general strategy for on-DNA synthesis of diverse C3-functionalized indole derivatives via indole π-activated alcohol formation followed ...
Shuting Zhong   +11 more
core   +1 more source

Multimodal Medical Image Protection Algorithm Based on Genetic Coding and Coupled Hyperchaotic Mapping

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] In order to ensure the security of multimodal medical images, a multimodal medical image protection algorithm based on genetic coding and coupled hyperchaotic mapping is proposed.
CHANG Ruiyun, FENG Xiufang, ZHANG Hao
doaj   +1 more source

Structure encoding in DNA

open access: yesJournal of Theoretical Biology, 2019
It is proposed that transposons and related long non–coding RNA define the fine structure of body parts. Although morphogens have long been known to direct the formation of many gross structures in early embryonic development, they do not have the necessary precision to define a structure down to the individual cellular level.
openaire   +2 more sources

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei [PDF]

open access: yes, 1992
Tissue-specific patterns of methylated deoxycytidine residues in the mammalian genome are preserved by postreplicative methylation of newly synthesized DNA. DNA methyltransferase (MTase) is here shown to associate with replication foci during S phase but
Heinz-Ulrich Weier   +14 more
core   +1 more source

Hash Based DNA Computing Algorithm for Image Encryption

open access: yesApplied Sciences, 2023
Deoxyribonucleic Acid (DNA) computing has demonstrated great potential in data encryption due to its capability of parallel computation, minimal storage requirement, and unbreakable cryptography.
Hongming Li   +3 more
doaj   +1 more source

Detection of beta-globin genes in the erythrocyte fraction in a patient with cervical cancer

open access: yesЯкутский медицинский журнал
The results of detection of DNA fragments encoding human beta-globin and human papillomavirus L1 protein in plasma and erythrocyte samples from a cervical cancer patient using real-time polymerase chain reaction (qPCR) are presented.
I. V. Kononova   +2 more
doaj   +1 more source

Gene-encoding DNA origami for mammalian cell expression

open access: yesNature Communications, 2023
DNA origami may enable more versatile gene delivery applications through its ability to create custom nanoscale objects. Here the authors show that genes folded in DNA origami with custom scaffolds express efficiently when delivered to mammalian cells ...
Jessica A. Kretzmann   +5 more
doaj   +1 more source

DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle

open access: yesScientific Reports, 2023
Each tissue has a dominant set of functional proteins required to mediate tissue-specific functions. Epigenetic modifications, transcription, and translational efficiency control tissue-dominant protein production.
Hideki Maehara   +20 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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