Results 81 to 90 of about 2,699,979 (303)
Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organism [PDF]
, 2011 This work is supported by the The Scottish Universities Life Sciences Alliance (SULSA)Single-stranded DNA-binding proteins (SSBs) play vital roles in all aspects of DNA metabolism in all three domains of life and are characterized by the presence of one ...
Skowyra, Agnieszka +4 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Journal of Extracellular Vesicles, 2014 The induction of an active immune response to control or eliminate tumours is still an unfulfilled challenge. We focused on plasmid DNA vaccines using an innovative approach whereby the antigen is expressed in association with extracellular vesicles (EVs)
Christine Sedlik +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
INNSE: Invertible neural network-based DNA image storage with self-correction encoding
Computational and Structural Biotechnology JournalDNA storage has become an alternative to silicon-based storage of media. However, when used to store multimodal data such as images, it fails to take full advantage of the characteristics of high correlation and variability present in such data, and ...
Yanfen Zheng +6 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Optical asymmetric image encryption using DNA through vortex beam encoding
Discover Applied SciencesOptical vortex beam has gained much attention in the field of information processing because of its inherent features, such as the infinite number of orthogonal modes.
Sonu Kumar Rao +3 more
doaj +1 more source
Cloning Gene Encoding Micronema 3 (Mic3) Protein of Tachyzoite Toxoplasma Gondii Local Isolate
Indonesian Journal of Biotechnology, 2005 Microneme 3 (MIC3) protein tachyzoites Toxoplasma gondii is one of protein which plays an important role during cell host invasion. Gene encoding MIC3 protein has been studied and it was suggested a potent vaccine candidate against Toxoplasma gondii ...
Wayan T. Artama +2 more
doaj +1 more source
MEI: The Music Encoding Initiative Guidelines (PDF)
, 2010 <p><strong>PDF versions of the Music Encoding Initiative Guidelines</strong></p><p> </p><p><a href="https://doi.org/10.5281/zenodo.10040125"><strong>2010-05</strong></a><strong>:
Music Encoding Initiative Working Group
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source