Results 91 to 100 of about 2,699,979 (303)

Text encryption through bio-inspired DNA and RNA sequencing.

open access: yesPLoS ONE
Cryptography is the technology of protecting information and communication by means of encoding the sending information. Existing methods often operate within predetermined mathematical structures which can be subject to pattern recognition and which are
Omar Fitian Rashid   +2 more
doaj   +1 more source

Searching for Genes of Lactococcus lactis subsp. lactis Encoding the Bacteriocin Nisin using DNA/DNA Hybridisation

open access: yesCzech Journal of Food Sciences, 2009
In this work, PCR primers P8 and P9 were used for amplification of a 320 bp long PCR product specific to the nisin gene. The PCR product was labelled with digoxigenine during amplification and used as a DNA probe for the screening of homologous DNA ...
M. Dušková   +3 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

MEI: The Music Encoding Initiative Guidelines (PDF)

open access: yes, 2012
<p><strong>PDF versions of the Music Encoding Initiative Guidelines</strong></p><p> </p><p><a href="https://doi.org/10.5281/zenodo.10040170"><strong>2012 (v2.0.0)</strong></a>< ...
Music Encoding Initiative
core   +1 more source

Small Circular Rep-Encoding Single-Stranded DNA Genomes in Peruvian Diarrhea Virome [PDF]

open access: yes, 2017
Metagenomic analysis of diarrhea samples revealed the presence of numerous human enteric viruses and small circular Rep-encoding single-stranded DNA (CRESS-DNA) genomes.
Deng, Xutao   +13 more
core   +1 more source

MEI: The Music Encoding Initiative Guidelines (PDF)

open access: yes, 2023
<p><strong>PDF versions of the Music Encoding Initiative Guidelines</strong></p><p> </p><p><a href="https://doi.org/10.5281/zenodo.10040258"><strong>5.0</strong></a><strong> <
Music Encoding Initiative
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Plasma-activated air mediates plasmid DNA delivery in vivo

open access: yesMolecular Therapy: Methods & Clinical Development, 2016
Plasma-activated air (PAA) provides a noncontact DNA transfer platform. In the current study, PAA was used for the delivery of plasmid DNA in a 3D human skin model, as well as in vivo.
Chelsea M Edelblute   +4 more
doaj   +1 more source

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