Results 151 to 160 of about 4,713,939 (389)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Lysis Buffers for Detecting Pork Content in Food Products

Indonesian Journal of Chemistry
The increasing number of counterfeit processed food products with non-halal ingredients, such as pork, has caused public concern about the halalness of Indonesian food products, especially in the Muslim community.
Ulfah Lailatul Khoiriah, Pramudja Baydillah, Raden Darmawan, Nasori Nasori, Fadlilatul Taufany, Setiyo Gunawan   +5 more
doaj   +1 more source

Optimization of DNA extraction from dental remains

Electrophoresis, 2019
Efficient DNA extraction procedures is a critical step involved in the process of successful DNA analysis of such samples. Various protocols have been devised for the genomic DNA extraction from human tissues and forensic stains, such as dental tissue ...
C. Cafiero, A. Re, E. Stigliano, E. Bassotti, R. Moroni, C. Grippaudo   +5 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

New Anastomosis Group F (AG-F) of binucleate Rhizoctonia causing root and stem rot of Pistacia vera

Journal of Crop Protection, 2017
A total of ten isolates of fungi with Rhizoctonia-like mycelia were obtained from infected roots and stems of Pistachio Pistacia vera grown in a commercial nursery in Rafsanjan, Iran, during the autumn of 2011.
Hossein Alaei, Saeed Molaei, Seyed Bagher Mahmoodi, Roohollah Saberi-Riseh   +3 more
doaj  

Ehrlichia ruminantium detection using efficient high-throughput molecular method. [0088] [PDF]

, 2017
In order to improve sample screening capacity and E. ruminantium molecular diagnostics, an automated DNA extraction method for Amblyomma ticks and a new qPCR targeting the pCS20 gene region were successfully developed.
Albina, Emmanuel, Bournez, Laure, Cangi, Nidia, Lefrançois, Thierry, Neves, Luis, Pinarello, Valérie, Vachiéry, Nathalie   +6 more
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

DNA Concentrations in the Human Cerebellum. Computation from Kinetics of Deoxyribose Extraction in Hot Acid. [PDF]

, 1983
Daniel N. Slatkin, Søren Løvtrup, Gerhard Schroll, Grete Wøien, Jan-Eric Berg, Thomas W. Dingle, Richard Vaughan Williams, Ramanathan Mahedevan   +7 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Exploring the hidden complexities of the colostrum and milk microbiome in livestock: emerging insights and challenges

Italian Journal of Animal Science
The introduction of advanced sequencing platforms has redefined our understanding of microbial communities, revealing their presence in environments long assumed to be sterile. This literature review explores the complex microbiota of colostrum and milk,
Diana Luise, Silvia Carta, Paola Cremonesi, Rosanna Marino, Bianca Castiglioni   +4 more
doaj   +1 more source