Results 171 to 180 of about 4,873,130 (388)

Exploring the hidden complexities of the colostrum and milk microbiome in livestock: emerging insights and challenges

Italian Journal of Animal Science
The introduction of advanced sequencing platforms has redefined our understanding of microbial communities, revealing their presence in environments long assumed to be sterile. This literature review explores the complex microbiota of colostrum and milk,
Diana Luise, Silvia Carta, Paola Cremonesi, Rosanna Marino, Bianca Castiglioni   +4 more
doaj   +1 more source

Ehrlichia ruminantium detection using efficient high-throughput molecular method. [0088] [PDF]

, 2017
In order to improve sample screening capacity and E. ruminantium molecular diagnostics, an automated DNA extraction method for Amblyomma ticks and a new qPCR targeting the pCS20 gene region were successfully developed.
Albina, Emmanuel, Bournez, Laure, Cangi, Nidia, Lefrançois, Thierry, Neves, Luis, Pinarello, Valérie, Vachiéry, Nathalie   +6 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Comparison of methods of DNA extraction from stream sediments [PDF]

, 1995
Laura G. Leff, J R Dana, J. Vaun McArthur, Lawrence J. Shimkets   +3 more
openalex   +1 more source

New Anastomosis Group F (AG-F) of binucleate Rhizoctonia causing root and stem rot of Pistacia vera

Journal of Crop Protection, 2017
A total of ten isolates of fungi with Rhizoctonia-like mycelia were obtained from infected roots and stems of Pistachio Pistacia vera grown in a commercial nursery in Rafsanjan, Iran, during the autumn of 2011.
Hossein Alaei, Saeed Molaei, Seyed Bagher Mahmoodi, Roohollah Saberi-Riseh   +3 more
doaj  

Ekstraksi Dna Collocalia Fuchiphaga Dengan Metode Phenol Chloroform Extraction Dari Berbagai Material Sumber Genetik [PDF]

, 2013
DNA extraction is the first important step in molecular study. The aim of this research was to compare DNA extraction protocols, PCE and extraction kit for each genetic material sources (blood and feathers).
Hendra, H. (Hendra), Heryanto, A. F. (Aditya), Riyanto, C. (Cellica), Suryaningtyas, N. W. (Natalia)   +3 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Efficiencies of recovery and extraction of trace DNA from non-porous surfaces [PDF]

, 2017
Ines Wood, Sophie Park, J. W. Tooke, Olutolani Smith, Ruth M. Morgan, Georgina E. Meakin   +5 more
openalex   +1 more source