Results 11 to 20 of about 2,239,481 (376)

A Geographically-Restricted but Prevalent Mycobacterium tuberculosis Strain Identified in the West Midlands Region of the UK between 1995 and 2008 [PDF]

, 2011
Background: We describe the identification of, and risk factors for, the single most prevalent Mycobacterium tuberculosis strain in the West Midlands region of the UK.Methodology/Principal Findings: Prospective 15-locus MIRU-VNTR genotyping of all M ...
A Fok, AD Jackson, AL Gibson, Andrea L. Gibson, Annette Wood, AR Moss, Babatunde Olowokure, CS Lambregts-van Weezenbeek, D Alland, D van Soolingen, DC Perlman, E. Grace Smith, G de Vries, Helen Jones, Ibrahim Abubakar, J Love, Jason T. Evans, JD van Embden, JE Oeltmann, Jonathan S. Mann, JT Evans, K Brudey, Laura Anderson, LC Lazzarini, LC Lazzarini, LS Cowan, MC Ruddy, MW Borgdorff, P Supply, P Supply, Pam Sonnenberg, Pere-Joan Cardona, Peter M. Hawkey, PM Hawkey, PM Small, R Frothingham, R Stavrum, Robert L. Serafino Wani, S Ghebremichael, Sarah Gardiner, SJ McNabb, SV Kik, Zaluckyj Sarah   +42 more
core   +15 more sources

SET1/MLL family of proteins: functions beyond histone methylation

Epigenetics, 2021
The SET1 family of enzymes are well known for their involvement in the histone 3 lysine 4 (H3K4) methylation, a conserved trait of euchromatin associated with transcriptional activation.
Jeyapal Sugeedha, Jyoti Gautam, Shweta Tyagi   +2 more
doaj   +1 more source

DNA fingerprints from fingerprints [PDF]

Nature, 1997
Forensic scientists regularly generate genetic profiles from old blood stains, seminal stains, vaginal swabs, hair, bone, urine and cigarette butts1,2,3,4,5,6. We show that an individual's genetic profile can now also be generated from swabs taken from objects touched by hands, providing a new tool for crime scene investigations.
Maxwell K. Jones, Roland A.H. van Oorschot   +1 more
openaire   +3 more sources

Sequence variations, flanking region mutations, and allele frequency at 31 autosomal STRs in the central Indian population by next generation sequencing (NGS)

Scientific Reports, 2021
Capillary electrophoresis-based analysis does not reflect the exact allele number variation at the STR loci due to the non-availability of the data on sequence variation in the repeat region and the SNPs in flanking regions.
Hirak Ranjan Dash, Kamlesh Kaitholia, R. K. Kumawat, Anil Kumar Singh, Pankaj Shrivastava, Gyaneshwer Chaubey, Surajit Das   +6 more
doaj   +1 more source

Therapeutic application of PPE2 protein of Mycobacterium tuberculosis in inhibiting tissue inflammation

EMBO Molecular Medicine, 2022
There is an increasing need to develop biological anti‐inflammatory agents that are more targeted, effective, and with lesser side effects as compared to conventional chemical drugs.
Ravi Pal, Madhu Babu Battu, Sangita Mukhopadhyay   +2 more
doaj   +1 more source

Epigenetic Regulation of Antifungal Drug Resistance

Journal of Fungi, 2022
In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple aspects of fungal biology ranging from development, phenotypic and morphological plasticity to antifungal drug resistance.
Sandip Patra, Mayur Raney, Aditi Pareek, Rupinder Kaur   +3 more
doaj   +1 more source

Authentication of Coffea arabica varieties through DNA fingerprinting and its significance for the coffee sector [PDF]

, 2020
Background: Locating the optimal varieties for coffee cultivation is increasingly considered a key condition for sustainable production and marketing.
Bertrand, Benoît, Krishnan, Sarada, Montagnon, Christophe, Pruvot-Woehl, Solène, Schilling, Timothy, Solano, William, Toniutti, Lucile   +6 more
core   +1 more source

Direct PCR amplification from saliva sample using non-direct multiplex STR kits for forensic DNA typing

Scientific Reports, 2021
Due to its proficiency to provide the most discriminating results for forensic applications, medical research and anthropological studies, multiplex PCR based STR analysis has been established as the most efficient technique in the forensic DNA analysis.
Pankaj Shrivastava, Toshi Jain, R. K. Kumawat   +2 more
doaj   +1 more source

DNA fingerprinting [PDF]

Nature, 1989
Abstract Hypervariable tandem-repetitive minisatellite regions of human DNA can be used to generate individual-specific DNA fingerprints. Validation studies have demonstrated the reliability of the analysis, the mode of inheritance of the minisatellites, and the unparalleled degree of individual specificity.
openaire   +4 more sources

Evaluation of diallelic STR markers with inter-population allelic database for their usefulness in paternity trios in the Central Indian population

Annals of Human Biology, 2021
Background Most of the forensic DNA laboratories have migrated to new generation STR kits of 6 dye chemistry with more than 20 autosomal STRs. The population-specific databases of such STR markers are lacking in many regions.
Hirak Ranjan Dash, Kamayani Vajpayee, Radhika Agarwal, Anubha Gang, Ritesh Shukla, Ankit Srivastava   +5 more
doaj   +1 more source