Results 31 to 40 of about 2,272,311 (259)

Highly efficient CRISPR-SaKKH tools for plant multiplex cytosine base editing

Crop Journal, 2020
Base editing, as an expanded clustered regularly interspaced short palindromic repeats (CRISPR)-Cas genome editing strategy, permits precise and irreversible nucleotide conversion. SaKKH, an efficient variant of a Cas9 ortholog from Staphylococcus aureus
Chengwei Zhang, Feipeng Wang, Si Zhao, Guiting Kang, Jinling Song, Lu Li, Jinxiao Yang   +6 more
doaj   +1 more source

Phosphatidylinositol 3-phosphate regulates iron transport via PI3P-binding CgPil1 protein

Cell Reports, 2023
Summary: Iron homeostasis, which is pivotal to virulence, is regulated by the phosphatidylinositol 3-kinase CgVps34 in the human fungal pathogen Candida glabrata.
Fizza Askari, Bhogadi Vasavi, Rupinder Kaur   +2 more
doaj   +1 more source

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C., Claassen, H.J.H.M., Majiwa, P.A.O., Pas, M.F.W., te   +3 more
core   +4 more sources

Xanthoferrin Siderophore Estimation from the Cell-free Culture Supernatants of Different Xanthomonas Strains by HPLC

Bio-Protocol, 2017
Xanthomonads can scavenge iron from the extracellular environment by secreting the siderophores, which are synthesized by the proteins encoded by xss (Xanthomonas siderophore synthesis) gene cluster.
Sheo Pandey, Prashantee Singh, Biswajit Samal, Raj Verma, Subhadeep Chatterjee   +4 more
doaj   +1 more source

Forensic features and phylogenetic analyses of the population of Nayagarh (Odisha), India using 23 Y-STRs

Annals of Human Biology, 2022
Aim The present study was designed to explore the STR diversity and genomic history of the inhabitants of Nayagarh district of Odisha, India. We also tested the proficiency of the most recent, new generation PowerPlexR Y23 multiplex system for forensic ...
Muktikanta Panda, Ramkishan Kumawat, Shivani Dixit, Awdhesh Narayan Sharma, Hari Shankar, Gyaneshwer Chaubey, Pankaj Shrivastava   +6 more
doaj   +1 more source

Candida glabrata: A Lot More Than Meets the Eye

Microorganisms, 2019
Candida glabrata is an opportunistic human fungal pathogen that causes superficial mucosal and life-threatening bloodstream infections in individuals with a compromised immune system. Evolutionarily, it is closer to the non-pathogenic yeast Saccharomyces
Kundan Kumar, Fizza Askari, Mahima Sagar Sahu, Rupinder Kaur   +3 more
doaj   +1 more source

Ectopic Expression of Rv0023 Mediates Isoniazid/Ethionamide Tolerance via Altering NADH/NAD+ Levels in Mycobacterium smegmatis

Frontiers in Microbiology, 2020
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) accounts for nearly 1.2 million deaths per annum worldwide. Due to the emergence of multidrug-resistant (MDR) Mtb strains, TB, a curable and avertable disease, remains one of the leading causes
Shailesh Kumar Gupta, Shailesh Kumar Gupta, Rajendra Kumar Angara, Suhail Yousuf, Chilakala Gangi Reddy, Chilakala Gangi Reddy, Akash Ranjan   +6 more
doaj   +1 more source

Identification of a locus associated with genic male sterility in maize via EMS mutagenesis and bulked-segregant RNA-seq

Crop Journal, 2021
Genic male sterility (GMS) is one of the most important resources for exploiting heterosis in crop breeding, so that identifying genomic loci regulating GMS is desirable.
Zi Shi, Wen Ren, Yanxin Zhao, Xiaqing Wang, Ruyang Zhang, Aiguo Su, Shuai Wang, Chunhui Li, Jiarong Wang, Shuaishuai Wang, Yunxia Zhang, Yulong Ji, Wei Song, Jiuran Zhao   +13 more
doaj   +1 more source

Molecular epidemiology of endemic Clostridium difficile infection [PDF]

, 2001
This is the first study to provide a comprehensive insight into the molecular epidemiology of endemic Clostridium difficile and particularly that associated with a recently recognized epidemic strain. We DNA fingerprinted all C.
Fawley, W.N., Wilcox, M.H.
core   +2 more sources

iTRAQ-based quantitative proteomic analysis provides insight into the drought-stress response in maize seedlings

Scientific Reports, 2022
Drought is a major abiotic stress that harms plant cell physiology and limits the growth and productivity of crops. Maize (Zea mays L.), one of the most drought-susceptible crops, is a major food source for humans and an important resource for industrial
Wen Ren, Zi Shi, Miaoyi Zhou, Bingbing Zhao, Hanshuai Li, Jiarong Wang, Ya Liu, Jiuran Zhao   +7 more
doaj   +1 more source