Results 181 to 190 of about 43,780 (231)

Molecular basis and functional consequences of the interaction between the base excision repair DNA glycosylase NEIL1 and RPA. [PDF]

J Biol Chem
Le Meur RA, Pecen TJ, Le Meur KV, Nagel ZD, Chazin WJ.   +4 more
europepmc   +1 more source

Structural and functional coupling in cross-linking uracil-DNA glycosylase UDGX. [PDF]

Biosci Rep
Liang C, Yang Y, Ning P, Chang C, Cao W.
europepmc   +1 more source

DCAF2 regulates the proliferation and differentiation of mouse progenitor spermatogonia by targeting p21 and thymine DNA glycosylase. [PDF]

Cell Prolif
Wei H, Wang Z, Huang Y, Gao L, Wang W, Liu S, Sun YL, Liu H, Weng Y, Fan HY, Zhang M.   +10 more
europepmc   +1 more source

[He<b>'</b>s Yangchao recipe ameliorates premature ovarian insuffi-ciency by regulating 8-oxoguanine DNA glycosylase 1 in mice]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Hu R, Zhao Y, Wu Y, Zhang Y, Liu Q, Lin F, Zhang Q, Miao C.   +7 more
europepmc   +1 more source

The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress. [PDF]

J Extracell Vesicles
Ma Y, Guo J, Rao H, Xin J, Song X, Liu R, Shao S, Hou J, Kong L, Hu Z, He L, Pan F, Guo Z.   +12 more
europepmc   +1 more source

Modulation of 8-Oxoguanine DNA Glycosylase 1 (OGG1) Alleviated Anemia Severity and Excessive Cytokines Release during Plasmodium berghei Malaria in Mice. [PDF]

Iran J Parasitol
Samaila A, Basir R, Abdul Aziz NAL, Alarabei AA, Gambo ML, Abdullah MA, Hussain MK, Nordin N, Majid RA.   +8 more
europepmc   +1 more source

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DNA glycosylase recognition and catalysis

Current Opinion in Structural Biology, 2004
DNA glycosylases are the enzymes responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Recent structural and biochemical results have provided novel insights into DNA damage recognition and repair. The basis of the recognition of the oxidative lesion 8-oxoguanine by two structurally unrelated DNA glycosylases ...
J Christopher, Fromme, Anirban, Banerjee, Gregory L, Verdine   +2 more
openaire   +4 more sources

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

Nature, 1996
Mispairs in DNA of guanine with uracil and thymine can arise as a result of deamination of cytosine and 5-methylcytosine, respectively. In humans such mispairs are removed by thymine-DNA glycosylase (TDG). By deleting the carboxy and amino termini of this enzyme we have identified a core region capable of processing G/U but not G/T mispairs.
Gallinari, P, Jiricny, J
openaire   +5 more sources

DNA glycosylases

Molecular and Cellular Biochemistry, 1982
Various DNA glycosylases exist, which initiate the first step in base-excision repair. A summary of the kinetic and physical characteristics of three classes of DNA glycosylases are presented here. The first class discussed, include glycosylases which recognize alkylated DNA.
S J, Caradonna, Y C, Cheng
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Thymine DNA glycosylase

2001
More than 50% of colon cancer-associated mutations in the p53 tumor suppressor gene are C-->T transitions. The majority of them locate in CpG dinucleotides and are thought to have arisen through spontaneous hydrolytic deamination of 5-methylcytosine. This deamination process gives rise to G.T mispairs that need to be repaired to G.C in order to avoid C-
Hardeland, U., Bentele, M., Lettieri, T., Steinacher, R., Jiricny, J., Schär, P.   +5 more
openaire   +3 more sources