Results 1 to 10 of about 1,090 (73)

Human uracil DNA N-glycosidase: studies in normal and repair defective cultured fibroblasts

open access: yesNucleic Acids Research, 1978
Uracil DNA N-glycosidase, an enzyme which participates in the excision of uracil from DNA, was measured in extracts from fibroblasts lines cultured from normal subjects, from several subjects with the genetic disease xeroderma pigmentosum, and from a subject with ataxia telangiectasia.
Urs Kühnlein   +2 more
exaly   +4 more sources

Enzymes from Micrococcus luteus involved in the initial steps of excision repair of spontaneous DNA lesions: uracil-DNA-glycosidase and apurinic-endonucleases

open access: yesNucleic Acids Research, 1978
Uracil-DNA-glycosidase that releases free uracil from single-stranded or double-stranded deaminated DNA and poly d(A-U) has been partially purified from Micrococcus luteus. The enzyme has a molecular weight of about 16,000 and can be separated from uracil-endonuclease and endonucleases (AP-endonucleases) specific for apurinic and apyrimidinic sites ...
N V, Tomlin   +2 more
exaly   +4 more sources

The Verrucomicrobia LexA-binding Motif: Insights into the Evolutionary Dynamics of the SOS Response

open access: yesFrontiers in Molecular Biosciences, 2016
The SOS response is the primary bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division and translesion synthesis.
Ivan Erill   +3 more
doaj   +1 more source

Structural basis for uracil removal from DNA by human SMUG1. [PDF]

open access: yesNat Commun
Ludäscher JM   +14 more
europepmc   +1 more source

Cadmium inhibits hSMUG1-mediated uracil excision: quantitative analysis and mitigation by <i>Ganoderma lucidum</i> extracts. [PDF]

open access: yesJ Enzyme Inhib Med Chem
Chang HL   +10 more
europepmc   +1 more source

A Single-Enzyme Activated CRISPR-Cas12a Nano System via Subtly Balanced dsDNA for Kinetic-Gated UDG Detection and Spatiotemporal Cellular Imaging. [PDF]

open access: yesAdv Sci (Weinh)
Dong K   +12 more
europepmc   +1 more source

B cell receptor stimulation inhibits class switch recombination through elevated DNA repair. [PDF]

open access: yesDNA Repair (Amst)
Maul RW   +8 more
europepmc   +1 more source

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