Results 31 to 40 of about 1,296 (134)

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, Volume 22, Issue 9, September 2025.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Integrierte chemo‐enzymatische Synthese des mRNA‐Impfstoff‐Bausteins N1‐Methylpseudouridintriphosphat

open access: yesAngewandte Chemie, Volume 137, Issue 34, August 18, 2025.
Pseudouridin‐5'‐triphosphat (ΨTP) und sein N1‐methyliertes Derivat (m1ΨTP) sind entscheidende Komponenten in der mRNA‐Impfstofftechnologie. Hier wird ein atomökonomischer, ertragreicher biokatalytischer Weg zur Synthese von ΨTP vorgestellt. Zudem wurde ein neuer chemo‐enzymatischer Weg für die m1ΨTP‐Synthese entwickelt.
Martin Pfeiffer   +4 more
wiley   +1 more source

Interactions between saporin, a ribosome-inactivating protein, and DNA: A study by atomic force microscopy [PDF]

open access: yes, 2005
Saporins are enzymes belonging to the PNAG class (polynucleotide: adenosine glycosidase), plant enzymes commonly known as ribosome-inactivating proteins (RIP), as a result of their property of irreversibly damaging eukaryotic ribosomes.
Pittaluga E.   +5 more
core   +2 more sources

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

open access: yesChemPlusChem, Volume 90, Issue 7, July 2025.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber   +3 more
wiley   +1 more source

Stimuli‐Responsive Silica Silanol Conjugates: Strategic Nanoarchitectonics in Targeted Drug Delivery

open access: yesSmall, Volume 20, Issue 39, September 26, 2024.
The silica surface silanol chemistry and its conjugation to different cargos through stimuli‐responsive linkers are highly desired. This review elucidates silica's surface chemistry, types of silanols, silanol number and chemistry, chemical and physical identification, functionalization, and stimuli‐responsive for precise drug delivery systems ...
Shan Mohanan   +4 more
wiley   +1 more source

A systemic antiviral resistance-inducing protein isolated from Clerodendrum inerme Gaertn. is a polynucleotide:adenosine glycosidase (ribosome-inactivating protein)

open access: yes, 1996
Two systemic antiviral resistance-inducing proteins, CIP-29 and CIP-34, isolated from Clerodendrum inerme Gaertn. leaves, were tested for ribosome-inactivating properties.
Ghosal-Chowdhury P.   +7 more
core   +2 more sources

RNA methylation‐related inhibitors: Biological basis and therapeutic potential for cancer therapy

open access: yesClinical and Translational Medicine, Volume 14, Issue 4, April 2024.
In this review, several common types of RNA modifications are reviewed, and the role of regulatory factors related to these modifications in cancer progression is discussed. Finally, the latest advances in small molecule inhibitors of these regulatory factors are especially reviewed. Abstract RNA methylation is widespread in nature. Abnormal expression
Huanxiang Chen   +9 more
wiley   +1 more source

Polynucleotide:adenosine glycosidase activity of ribosome-inactivating proteins: Effect on DNA, RNA and poly(A)

open access: yes, 1997
Ribosome-inactivating proteins (RIP) are a family of plant enzymes for which a unique activity was determined: rRMA N-glycosidase at a specific universally conserved position, A4324 in the case of rat ribosomes.
Valbonesi P.   +5 more
core   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +2 more sources

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