Results 51 to 60 of about 1,466,903 (122)

Identification of human herpesvirus 6 uracil-DNA glycosylase

, 1994
Uracil-DNA glycosylase encoded in many species functions as a DNA repair enzyme that removes uracil residues from DNA. To investigate he potential function of uracil-DNA glycosylase ncoded by human herpes-virus 6 (HHV-6), we sequenced a DNA clone (pSTY09)
Yuji Isegawa, Shigeo Sato, Takeshi Yamamoto, Koichi Yamanishi   +3 more
core  

Novel inhibition of archaeal family-D DNA polymerase by uracil.

, 2013
International audienceArchaeal family-D DNA polymerase is inhibited by the presence of uracil in DNA template strands. When the enzyme encounters uracil, following three parameters change: DNA binding increases roughly 2-fold, the rate of polymerization ...
Ishino, Yoshizumi, Henneke, Ghislaine, Gilroy, Louise, Richardson, Tomas T, Connolly, Bernard A   +4 more
core   +1 more source

Register Shifts in Uracil-Damaged DNA

Uracil is a highly mutagenic and common lesion of DNA, which is caused by misincorporation or spontaneous deaminating of cytosine. Uracil will spontaneously base flip, breaking its Watson-Crick hydrogen bonds and base stacking and leaving the helix stack.
Tran, Megan
core  

Genetic studies with a uracil DNA glycosylase biosensor support a role for mitochondrial UNG1 in nuclear uracil repair. [PDF]

Nucleic Acids Res
Lin YT, Lott AM, Liu X, Abdulbaki L, Chen Y, Carpenter MA, Harris RS.   +6 more
europepmc   +1 more source

Metabolic Engineering of Escherichia coli for Efficient Production of Pseudouridine. [PDF]

ACS Omega, 2023
Zhou M, Tang R, Wei L, Wang J, Qi H.
europepmc   +1 more source

Cadmium inhibits hSMUG1-mediated uracil excision: quantitative analysis and mitigation by <i>Ganoderma lucidum</i> extracts. [PDF]

J Enzyme Inhib Med Chem
Chang HL, Fang CH, Chang HL, Lee YF, Hsu WL, Chang JH, Chien MH, Goodman SD, Chang SY, Fang WH, Su KY.   +10 more
europepmc   +1 more source

A Single-Enzyme Activated CRISPR-Cas12a Nano System via Subtly Balanced dsDNA for Kinetic-Gated UDG Detection and Spatiotemporal Cellular Imaging. [PDF]

Adv Sci (Weinh)
Dong K, Hu H, Wang H, Zheng Z, Cheng S, Shu W, Liu R, Xin X, Huang S, Qian D, Xiao X, Fu Q, Wang H.   +12 more
europepmc   +1 more source

B cell receptor stimulation inhibits class switch recombination through elevated DNA repair. [PDF]

DNA Repair (Amst)
Maul RW, McFleder RL, Cao Z, Norton DD, Ridani J, Barbulescu P, Martin A, Di Noia JM, Gearhart PJ.   +8 more
europepmc   +1 more source

UNG-RPA interaction governs the choice between high-fidelity and mutagenic uracil repair. [PDF]

Nucleic Acids Res
Mu Y, Chen Z, Plummer JB, Zelazowska MA, Dong Q, Krug LT, McBride KM.   +6 more
europepmc   +1 more source

Noncatalytic surface electrostatic networks tune thermolability in uracil-DNA glycosylase. [PDF]

J Biol Chem
Simões RSM, Teodoro JS, Alves VD, Carvalho AL, Fontes CMGA, Bule P.   +5 more
europepmc   +1 more source