Can biowarfare agents be defeated with light? [PDF]
Biological warfare and bioterrorism is an unpleasant fact of 21st century life. Highly infectious and profoundly virulent diseases may be caused in combat personnel or in civilian populations by the appropriate dissemination of viruses, bacteria, spores,
de Sousa, Marcelo Victor Pires +6 more
core +1 more source
DNA Damage and Its Links to Neurodegeneration [PDF]
The integrity of our genetic material is under constant attack from numerous endogenous and exogenous agents. The consequences of a defective DNA damage response are well studied in proliferating cells, especially with regards to the development of ...
Madabhushi, Ram +2 more
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UV-radiation-induced formation of DNA bipyrimidine photoproducts in Bacillus subtilis endospores and their repair during germination [PDF]
The spore photoproduct (SP) is the main DNA lesion after UV-C irradiation, and its repair is crucial for the resistance of spores to UV. The aims of the present study were to assess the formation and repair of bipyrimidine photoproducts in spore DNA of ...
Erko Stackebrandt +7 more
core +2 more sources
New DNA Repair and Demethylation Functions in Uracil DNA Glycosylase Superfamily [PDF]
Uracil-DNA glycosylase (UDG) superfamily, which consists of several groups of enzymes that recognize the damaged DNA bases and initiate the base excision repair (BER) pathway, is most important in dealing with DNA deamination and other base modifications.
Chang, Chenyan
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Studies of Trans-N-Glycosidase of Thermobacter Acidophilus and its Inhibition by 6-Azathymidine [PDF]
[From the Introduction] The purpose of this investigation was to purify the enzyme trans-N-glycosidase from T. acidophilus and to study its specificity, optimum pH, and the effect of various other compounds, particularly azathymine and azathymidine, upon
Marsh, John C.
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The cytotoxic activity of ribosome-inactivating protein saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities [PDF]
Saporin-6 produced by the plant Saponaria officinalis belongs to the family of single chain ribosome-inactivating proteins. It potently inhibits protein synthesis in eukaryotic cells, by cleaving the N-glycosidic bond of a specific adenine in 28 S rRNA ...
Bagga, Shveta +2 more
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UEG Week 2025 Oral Presentations
United European Gastroenterology Journal, Volume 13, Issue S8, Page S7-S188, October 2025.
wiley +1 more source
The Application of Multi-dimensional Fluorescence Imaging to Microfluidic Systems
This thesis describes the application of multidimensional fluorescence imaging to microfluidic systems. The work focuses on time- and polarisation-resolved fluorescence microscopy to extract information from microchannel environments.
Robinson, Tom, Robinson, Tom
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DNA N-glycosidases: properties of uracil-DNA glycosidase from Escherichia coli.
T, Lindahl +4 more
openaire +2 more sources
The Evolutionary Diversity of Uracil DNA Glycosylase Superfamily [PDF]
Uracil DNA glycosylase (UDG) is a crucial member in the base excision (BER) pathway that is able to specially recognize and cleave the deaminated DNA bases, including uracil (U), hypoxanthine (inosine, I), xanthine (X) and oxanine (O).
Li, Jing
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