Results 121 to 130 of about 1,489,376 (287)
Cell Reports, 2018 Summary: R-loops comprise an RNA/DNA hybrid and displaced single-stranded DNA. They play important biological roles and are implicated in pathology. Even so, proteins recognizing these structures are largely undefined.
Agnese Cristini +3 more
doaj +1 more source
DNA Helicases used in this study.
, 2014 DNA Helicases used in this study.
Avvaru N. Suhasini (663612) +7 more
core +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Integrating Structural, Biochemical, and Cellular Perspectives on the TFIIH Helicases XPB and XPD
BiomoleculesXeroderma pigmentosum group B (XPB/ERCC3) and group D (XPD/ERCC2) helicases are integral components of the transcription factor IIH (TFIIH) complex, coordinating DNA unwinding during transcription initiation and nucleotide excision repair (NER).
Marco Bravo, Li Fan
doaj +1 more source
Helicase promotes replication re-initiation from an RNA transcript
Nature Communications, 2018 During DNA replication, replicative helicases play an essential role for DNA unwinding to occur. Here the authors find that bacteriophage T7 helicase is also involved in replication re-initiation by interacting with a non-replicating DNAP and increasing ...
Bo Sun +5 more
doaj +1 more source
Insight into the biochemical mechanism of DNA helicases provided by bulk-phase and single-molecule assays. [PDF]
Methods, 2022 Bianco PR.
europepmc +1 more source
Epileptic Disorders, EarlyView.Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by refractory seizures and frequently recurring epileptic activity with neurodevelopmental delay or regression that usually begin in early life. We aimed to define the relationship between electroclinical features and etiology, as well as the genotype–phenotype ...
Burcu Yaman +7 more
wiley +1 more source
Special Issue: DNA Helicases: Mechanisms, Biological Pathways, and Disease Relevance. [PDF]
Genes (Basel), 2021 Brosh RM.
europepmc +1 more source
Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy
Equine Veterinary Journal, EarlyView.Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan +4 more
wiley +1 more source
Up-regulated genes annotated as DNA helicases.
, 2016 Up-regulated genes annotated as DNA helicases.
John W. Whitaker (728679) +2 more
core +1 more source