Results 171 to 180 of about 1,489,376 (287)

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Subunit Communication within Dimeric SF1 DNA Helicases. [PDF]

J Mol Biol
Nguyen B, Hsieh J, Fischer CJ, Lohman TM.   +3 more
europepmc   +1 more source

Special Methods collection on DNA helicases. [PDF]

Methods, 2016
Brosh RM.
europepmc   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Massive contractions of myotonic dystrophy type 2-associated CCTG tetranucleotide repeats occur via double-strand break repair with distinct requirements for DNA helicases. [PDF]

G3 (Bethesda)
Papp D, Hernandez LA, Mai TA, Haanen TJ, O'Donnell MA, Duran AT, Hernandez SM, Narvanto JE, Arguello B, Onwukwe MO, Mirkin SM, Kim JC.   +11 more
europepmc   +1 more source

The Saccharomyces cerevisiae Hrq1 and Pif1 DNA helicases synergistically modulate telomerase activity in vitro. [PDF]

J Biol Chem, 2018
Nickens DG, Rogers CM, Bochman ML.
europepmc   +1 more source

RNA activation in insects: From emerging evidence to molecular applications

Insect Molecular Biology, EarlyView.
Canonical RNA activation involves small RNAs interacting with promoter sequences, but there is also evidence of non‐canonical RNAa in eukaryotes. Emerging evidence suggests the presence of RNAa in insects. RNAa can be utilised as a tool for functional genomic studies in insects.
Sassan Asgari
wiley   +1 more source

Single-molecule sorting of DNA helicases. [PDF]

Methods, 2016
Bain FE, Wu CG, Spies M.
europepmc   +1 more source

Expanding the Clinical Spectrum of DHX30‐Related Neurodevelopmental Disorder: A Case Report and a Scoping Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Whole exome sequencing (WES) has improved diagnostic rates for neurodevelopmental disorders (NDDs) while introducing challenges in novel variant interpretation. DHX30‐related NDD (DHX30‐NDD) is a recently described condition with an evolving phenotypic spectrum.
Nattaporn Tassanakijpanich, Areerat Hnoonual, Oradawan Plong‐On, Pornprot Limprasert   +3 more
wiley   +1 more source