Results 181 to 190 of about 47,217 (278)
Dna2 initiates resection at clean DNA double-strand breaks [PDF]
Hunter, Tony +4 more
core +2 more sources
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri +13 more
wiley +1 more source
Massive contractions of myotonic dystrophy type 2-associated CCTG tetranucleotide repeats occur via double-strand break repair with distinct requirements for DNA helicases. [PDF]
Papp D +11 more
europepmc +1 more source
The Saccharomyces cerevisiae Hrq1 and Pif1 DNA helicases synergistically modulate telomerase activity in vitro. [PDF]
Nickens DG, Rogers CM, Bochman ML.
europepmc +1 more source
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte +10 more
wiley +1 more source
ABSTRACT To enhance clinicians' understanding of Sifrim‐Hitz‐Weiss syndrome (SIHIWES), this study investigated the clinical phenotypes, genetic characteristics, and response to growth hormone therapy in a patient. A case of a patient with global developmental delay and distinctive facial features is presented.
Jianmei Zhang +6 more
wiley +1 more source
Direct Fluorescent Imaging of Translocation and Unwinding by Individual DNA Helicases. [PDF]
Pavankumar TL +2 more
europepmc +1 more source
Abstract Efforts are underway to increase the efficiency and precision of selection hop (Humulus lupulus L.) breeding using genomics. Little is known, however, about the genetic control of important traits like α‐and β‐acids contents, oil content, and cone morphological characteristics, all of which play an important role in determining the utility and
Shaun J. Clare +2 more
wiley +1 more source
Abstract Flag leaf morphology (FLM) is a critical determinant of wheat (Triticum aestivum L.) photosynthetic efficiency and grain yield. Chinese endemic wheat, a unique genetic reservoir formed by long‐term adaptation to diverse and heterogeneous environments in China, harbors abundant, untapped allelic variation for traits related to environmental ...
Md Nahibuzzaman Lohani +12 more
wiley +1 more source

