Results 101 to 110 of about 337,826 (349)
Role of the ubiquitin-selective CDC-48/UFD-1/NPL-4 chaperone in DNA replication [PDF]
, 2012 Faithful transmission of genomic information requires tight spatiotemporal regulation of DNA replication factors. Posttranslational modifications, such as ubiquitylation, constitute a fast and effective mechanism to control such complex protein function.
Franz, André
core
Advanced Functional Materials, EarlyView.A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen +17 more
wiley +1 more source
Frontiers in Plant Science, 2015 The DNA double-strand break (DSB) is a critical type of damage, and can be induced by both endogenous sources (e.g. errors of oxidative metabolism, transposable elements, programmed meiotic breaks, or perturbation of the DNA replication fork) and ...
Tomoyuki eFurukawa +3 more
doaj +1 more source
A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensivity in a patient with xeroderma pigmentosum [PDF]
, 2010 Background: Radiotherapy-induced DNA double-strand breaks (DSBs) are critical cytotoxic lesions. Inherited defects in DNA DSB repair pathways lead to hypersensitivity to ionising radiation, immunodeficiency and increased cancer incidence.
Abbaszadeh, Fatemah +9 more
core +1 more source
Human DNA ligases in replication and repair
DNA Repair, 2020 To ensure genome integrity, the joining of breaks in the phosphodiester backbone of duplex DNA is required during DNA replication and to complete the repair of almost all types of DNA damage. In human cells, this task is accomplished by DNA ligases encoded by three genes, LIG1, LIG3 and LIG4.
Annahita Sallmyr +4 more
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee +9 more
wiley +1 more source
Efficient assembly of very short oligonucleotides using T4 DNA Ligase
BMC Research Notes, 2010 Background In principle, a pre-constructed library of all possible short oligonucleotides could be used to construct many distinct gene sequences. In order to assess the feasibility of such an approach, we characterized T4 DNA Ligase activity on short ...
Holt Robert A +2 more
doaj +1 more source
Holliday junction resolvase in Schizosaccharomyces pombe has identical endonuclease activity to the CCE1 homologue YDC2 [PDF]
, 1998 A novel Holliday junction resolving activity has been identified in fractionated cell extracts of the fission yeast Schizosaccharomyces pombe . The enzyme catalyses endonucleolytic cleavage of Holliday junction-containing chi DNA and synthetic four-way ...
Keeley, A, Oram, M, Tsaneva, IR
core +2 more sources
Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles
Advanced Healthcare Materials, EarlyView.Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande +2 more
wiley +1 more source
DNA Ligase I Is Not Essential for Mammalian Cell Viability
Cell Reports, 2014 Summary: Of the three DNA ligases present in all vertebrates, DNA ligase I (Lig1) has been considered essential for ligating Okazaki fragments during DNA replication and thereby essential for cell viability.
Li Han +3 more
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