Results 231 to 240 of about 354,326 (330)

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo   +12 more
wiley   +1 more source

The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer. [PDF]

open access: yesIn Vivo
Deng Y   +12 more
europepmc   +1 more source

NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV. [PDF]

open access: yesNucleic Acids Res, 2020
Zhao B   +3 more
europepmc   +1 more source

Ligase do DNA [PDF]

open access: yesRevista de Ciência Elementar, 2014
openaire   +1 more source

Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias

open access: yesAdvanced Science, EarlyView.
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei   +32 more
wiley   +1 more source

Home - About - Disclaimer - Privacy