Results 241 to 250 of about 2,162,763 (370)

SUMOylation of SETD8 Promotes Tumor Growth by Methylating and Stabilizing MYC in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer (BC), MYC serves as a novel substrate of SETD8 to be methylated at lysine 412, which enhances MYC protein stability by preventing the CHIP‐mediated degradation and ultimately promotes tumor growth. SUMOylation of SETD8 leads to SETD8 stabilization and enhances MYC methylation.
Xia Zhang, Zhenxuan Chen, Xiaobo He, Jingxuan Wang, Jianliang Zhong, Yezi Zou, Xianchong Zheng, Yujie Lin, Ruhua Zhang, Tiebang Kang, Liwen Zhou, Yuanzhong Wu   +11 more
wiley   +1 more source

New Constructions of Reversible DNA Codes [PDF]

arXiv
DNA codes have many applications, such as in data storage, DNA computing, etc. Good DNA codes have large sizes and satisfy some certain constraints. In this paper, we present a new construction method for reversible DNA codes. We show that the DNA codes obtained using our construction method can satisfy some desired constraints and the lower bounds of ...
arxiv  

Fluorescence-, isotope- or biotin-labeling of the 5'-end of single-stranded DNA/RNA using T4 RNA ligase [PDF]

, 1997
Yohei Kinoshita, Koichi Nishigaki, Yuzuru Husimi   +2 more
openalex   +1 more source

Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination

Proceedings of the National Academy of Sciences of the United States of America, 2016
Shahnaz Masani, Li Han, K. Meek, Kefei Yu   +3 more
semanticscholar   +1 more source

PDCD11 Stabilizes C‐MYC Oncoprotein by Hindering C‐MYC‐SKP2 Negative Feedback Loop to Facilitate Progression of p53‐Mutant Breast and Colon Malignancies

Advanced Science, EarlyView.
PDCD11 overexpression highly correlates to poor prognosis in p53‐mutant breast and colon cancers. Through interaction with C‐MYC in the nucleoplasm, PDCD11 hinders C‐MYC‐induced SKP2 from binding to the C‐MYC MB2 domain for ubiquitination, thereby stabilizing C‐MYC to drive tumor progression.
Li Ding, Wei Ni, Yichao Ma, Lin Xu, Zhiping Zhang, Kai Liao, Jingwen Li, Xinyu Mei, Zhun Wang, Huiqian Ge, Jiajia Li, Dong Tang, Xinyue Zhang   +12 more
wiley   +1 more source

A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation

BMC Microbiology
Background The ATP-dependent DNA ligase Lig E is present as an accessory DNA ligase in numerous proteobacterial genomes, including many disease-causing species.
Jolyn Pan, Avi Singh, Kyrin Hanning, Joanna Hicks, Adele Williamson   +4 more
doaj   +1 more source

An etoposide-induced block in vaccinia virus telomere resolution is dependent on the virus-encoded DNA ligase [PDF]

, 1995
A M DeLange, Michael Carpenter, Judy Choy, V E Newsway   +3 more
openalex   +1 more source

Electrochemical‐Genetic Programming of Protein‐Based Magnetic Soft Robots for Active Drug Delivery

Advanced Science, EarlyView.
This manuscript presents a protein‐based soft robot for active drug delivery. Stimuli‐responsive protein is rationally designed and processed into the substrate of robots. Superparamagnetic Fe3O4 nanoparticles are patterned on the substrate using an electrochemical method, enabling the robot to respond to external physical fields.
Hang Zhao, Bo Yu, Dingyi Yu, Ting Ji, Kexin Nie, Jingyi Tian, Xinchen Shen, Kaiyue Zhang, Junhan Ou, Xinyi Yang, Dongfang Xiao, Qi Zhou, Wenwen Huang   +12 more
wiley   +1 more source

Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex*

Journal of Biological Chemistry, 2016
Zhimin Peng, Zhongping Liao, Y. Matsumoto, A. Yang, A. Tomkinson   +4 more
semanticscholar   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

Advanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang, Jianwei Zhu, Jinyi Zhou, Jinyang Li, Min Wang, Yuqi Wu, Danshan Zhao, Xiancheng Chen, Xiaoyuan Chen, Yuetong Wang, Jianhua Zou   +10 more
wiley   +1 more source