Results 241 to 250 of about 337,826 (349)

Altered DNA ligase activity in human disease. [PDF]

Mutagenesis, 2020
Tomkinson AE, Naila T, Khattri Bhandari S.   +2 more
europepmc   +1 more source

An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex. [PDF]

Nucleic Acids Res, 2021
Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE.   +9 more
europepmc   +1 more source

Role of DNA Ligase in the Illegitimate Recombination That Generates λbio-Transducing Phages in Escherichia coli [PDF]

, 2001
Masaaki Onda, Junko Yamaguchi, Katsuhiro Hanada, Yasuo Asami, Hideo Ikeda   +4 more
openalex   +1 more source

A Two‐Component Pseudo‐Icosahedral Protein Nanocompartment with Variable Shell Composition and Irregular Tiling

Advanced Science, EarlyView.
The structure and assembly principles of a two‐component encapsulin nanocompartment shell are reported. The two‐component protein compartment self‐assembles from two distinct HK97‐fold shell proteins into a pseudo‐icosahedral protein shell with variable composition and irregular tiling.
Cassandra A. Dutcher, Michael P. Andreas, Tobias W. Giessen   +2 more
wiley   +1 more source

The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer. [PDF]

In Vivo
Deng Y, Ke TW, Yueh TC, Chin YT, Wang YC, Hung YC, Mong MC, Yang YC, Wu WT, Chang WS, Gu J, Bau DT, Tsai CW.   +12 more
europepmc   +1 more source

NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV. [PDF]

Nucleic Acids Res, 2020
Zhao B, Naila T, Lieber MR, Tomkinson AE.   +3 more
europepmc   +1 more source

DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide insertion products in base excision repair. [PDF]

J Biol Chem, 2021
Kamble P, Hall K, Chandak M, Tang Q, Çağlayan M.   +4 more
europepmc   +1 more source

Optimised sample DNA preparation for detection of Chlamydia trachomatis in synovial tissue by polymerase chain reaction and ligase chain reaction [PDF]

, 2001
Julia Freise, Herv�e C. G�erard, Tania Bunke, Judith A. Whittum‐Hudson, H. Zeidler, L Köhler, Alan P. Hudson, Jens G. Kuipers   +7 more
openalex   +1 more source

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
wiley   +1 more source

Facile Splint-Free Circularization of ssDNA with T4 DNA Ligase by Redesigning the Linear Substrate to Form an Intramolecular Dynamic Nick. [PDF]

Biomolecules
Sun W, Hu K, Liu M, Luo J, An R, Liang X.   +5 more
europepmc   +1 more source