Results 251 to 260 of about 337,230 (276)
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Eukaryotic DNA Ligases and DNA Repair
1998The correct joining of appropriate DNA ends is a fundamental step in many important reactions within the cell and a number of enzymes have been identified which perform these end-joining reactions. Some enzymes execute a ligation step as an intermediate of their overall reaction mechanism; DNA topoisomerases are a prime example of this type of activity
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E3 ligase ligand chemistries: from building blocks to protein degraders
Chemical Society Reviews, 2022Izidor Sosi +2 more
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E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points
Frontiers in Chemistry, 2021Aleša Bricelj +2 more
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SCF ubiquitin ligase-targeted therapies
Nature Reviews Drug Discovery, 2014Julia K Pagan, Michele Pagano
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Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide
Nature, 2014Eric S Fischer +2 more
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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
Nature, 2004L Aravind +2 more
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Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase
Nature, 2016Georg Petzold, Eric S Fischer
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