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Interaction of β-L-Adenosine-5′-triphosphate (L-ATP) with Human Deoxycytidine Kinase, Human DNA Primase and T4 DNA Ligase: Does the Chance Direct Enzymatic Enantioselectivity?

Nucleosides and Nucleotides, 1999
We demonstrate that L-ATP: 1) as well as its natural D-enantiomer, acts as a phosphate donor in the reaction catalysed by human deoxycytidine kinase; 2) inhibits human DNA-primase and the ATP-dependent T4 DNA ligase. Thus, the lack of enantioselectivity of the enzymes is more frequent than it was believed a few years ago and we suggest that it would ...
A, Verri   +6 more
openaire   +2 more sources

ATP-type DNA ligase requires other proteins for its activity in vitro and its operon components for radiation resistance in Deinococcus radiodurans in vivo

Biochemistry and Cell Biology, 2010
A multiprotein DNA processing complex isolated from Deinococcus radiodurans contains the DNA repair protein PprA, an ATP-type DNA repair ligase (LigB) encoded by the drB0100 gene, and protein kinase activity. An ATP-dependent DNA end-joining activity was detected in the complex.
Swathi, Kota   +3 more
openaire   +2 more sources

ATP-DEPENDENT DNA LIGASE

2021
STRIBERNY BERND KETELSEN   +2 more
openaire   +2 more sources

Interaction of beta-L-adenosine-5 '-triphosphate (L-ATP) with human deoxycytidine kinase, human DNA primase and T4 DNA ligase: Does the chance direct enzymatic enantioselectivity?

1999
We demonstrate that L-ATP: 1) as well as its natural D-enantiomer, acts as a phosphate donor in the reaction catalysed by human deoxycytidine kinase; 2) inhibits human DNA-primase and the ATP-dependent T4 DNA ligase. Thus, the lack of enantioselectivity of the enzymes is more frequent than it was believed a few years ago and we suggest that it would ...
Verri A   +5 more
openaire   +1 more source

ATP-dependent DNA ligase fromThermococcussp. 1519 displays a new arrangement of the OB-fold domain

Acta Crystallographica Section F: Structural Biology Communications, 2012
Ekaterina Bezsudnova   +2 more
exaly  

ATP-dependent DNA ligase fromArchaeoglobus fulgidusdisplays a tightly closed conformation

Acta Crystallographica Section F: Structural Biology Communications, 2009
Se Won Suh, Sang Jae Lee, Hyoun Sook Kim
exaly  

Characterization of Bacteriophage T3 DNA Ligase

Journal of Biochemistry, 2004
Liang Cai
exaly  

DNA-based ATP sensing

TrAC - Trends in Analytical Chemistry, 2016
Xi Chen, Yiru Wang, Chunshui Lin
exaly  

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