Results 241 to 250 of about 1,734,103 (274)

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

E3 Ligases and Deubiquitinases in Controlling High-Mobility Group Box (HMGB) Protein Functions. [PDF]

Int J Mol Sci
Chikhirzhina EV, Tomilin AN, Tsimokha AS.   +2 more
europepmc   +1 more source

Application of Proximity-Labeling Techniques in Plants: A Review of Successful Cases. [PDF]

Int J Mol Sci
Yang Z, Yang S, Meng Q.
europepmc   +1 more source

E3 ubiquitin ligases in neurodegenerative diseases. [PDF]

Mil Med Res
Hou DL, Ho J, Guan T, Dong XX, Zeng L, Sanders LH, Wu YC, Tan EK, Zhou ZD.   +8 more
europepmc   +1 more source

From mechanisms to therapies: exploiting epigenetic and post-translational modifications of mitochondrial quality control in diabetic kidney disease. [PDF]

Front Endocrinol (Lausanne)
Zhao DM, Yan ZH, Yu YY, Zhang YY, Luan ZQ.   +4 more
europepmc   +1 more source

HSV-1 origin binding protein UL9 forms intermolecular DNA tethers and intramolecular DNA loops. [PDF]

Nat Commun
Meier AF, Vuckovic J, Girvan P, Jalal ASB, Cutts E, Brophy T, Ambrose B, Rueda DS.   +7 more
europepmc   +1 more source

Photothermal therapy triggering organelle stress and metabolic reprogramming to potentiate antitumor immunity. [PDF]

Front Immunol
Chen L, Zhang H, Wang Y, Feng X, Hou Y, Su Q.   +5 more
europepmc   +1 more source

Biochemical characterization of an ATP-dependent DNA ligase from the hyperthermophilic crenarchaeon Sulfolobus shibatae

Extremophiles, 2002
A gene encoding a putative ATP-dependent DNA ligase was identified in the genome of the hyperthermophilic archaeon Sulfolobus shibatae and expressed in Escherichia coli. The 601 amino acid recombinant polypeptide was a monomeric protein capable of strand joining on a singly nicked DNA substrate in the presence of ATP ( K(m)=34 micro mu) and a divalent ...
Xiaoqin, Lai, Hongbing, Shao, Fuying, Hao, Li, Huang   +3 more
exaly   +4 more sources

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The α-thio and/or β-γ-hypophosphate analogs of ATP as cofactors of T4 DNA ligase

Bioorganic Chemistry, 2016
T4 DNA ligase is one of the most commonly used enzymes for in vitro molecular research and a useful model for testing the ligation mechanism of ATP-dependent DNA ligation. To better understand the influence of phosphate group modifications in the ligation process, a series of ATP analogs were tested as cofactors.
Arkadiusz Chworos, Roza Pawlowska, Barbara Nawrot   +2 more
exaly   +3 more sources

A sensitive ligase-based ATP electrochemical assay using molecular beacon-like DNA

Biosensors and Bioelectronics, 2010
A sensitive and selective ligase-based signal-on electrochemical sensing method for adenosine-5'-triphosphate (ATP) detection had been developed using molecular beacon (MB)-like DNA. In this method, the biotin-tagged MB-like DNA was self-assembled onto a gold electrode to form a stem-loop structure by means of facile gold-thiol chemistry, which ...
Kemin Wang, Yonghong Wang, Xiaoxiao He   +2 more
exaly   +3 more sources