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Molecular Logic Gates Connected Through DNA Four-Way Junctions
Angewandte Chemie - International Edition, 2010 (Figure Presented) Simply logical: This study introduces connectable molecular logic gates made of DNA. Transfer of oligonucleotide input/ output signals from gate to gate is achieved by the formation of complexes that contain DNA four-way junctions when
Dmitry M Kolpashchikov
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DNA Computing: NOT Logic Gates See the Light
ACS Synthetic Biology, 2021DNA-based Boolean logic gates (for example, AND, OR, and NOT) can be assembled into complex computational circuits that generate an output signal in response to specific patterns of oligonucleotide inputs. However, the fundamental nature of NOT gates, which convert the absence of an input into an output, makes their implementation within DNA-based ...
Cole Emanuelson +2 more
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Multivalued Logic Gates Based on DNA
Chemistry - A European Journal, 2011Fang Pu, Xinjian Yang, Jinsong Ren
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Molecular Logic Gates for DNA Analysis: Detection of Rifampin Resistance in M. Tuberculosis DNA
Angewandte Chemie - International Edition, 2012 Elementary, Dr. Watson! A combination of YES and OR logic gates was applied to differentiate between DNA sequences of wild-type and rifampin-resistant (Rifr) Mycobacterium tuberculosis (Mtb) in a multiplex real-time fluorescent assay.
Dmitry M Kolpashchikov, Evan M Cornett
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Journal of the American Chemical Society, 2004
A conceptually new logic gate based on DNA has been devised. Methoxybenzodeazaadenine ((MD)A), an artificial nucleobase which we recently developed for efficient hole transport through DNA, formed stable base pairs with T and C. However, a reasonable hole-transport efficiency was observed in the reaction for the duplex containing an (MD)A/T base pair ...
Okamoto, A, Tanaka, K, Saito, I
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A conceptually new logic gate based on DNA has been devised. Methoxybenzodeazaadenine ((MD)A), an artificial nucleobase which we recently developed for efficient hole transport through DNA, formed stable base pairs with T and C. However, a reasonable hole-transport efficiency was observed in the reaction for the duplex containing an (MD)A/T base pair ...
Okamoto, A, Tanaka, K, Saito, I
openaire +2 more sources
Connectable DNA Logic Gates: OR and XOR Logics
Chemistry – An Asian Journal, 2011AbstractModern computer processors are based on semiconductor logic gates connected to each other in complex circuits. This study contributes to the development of a new class of connectable logic gates made of DNA in which the transfer of oligonucleotide fragments as input/output signals occurs upon hybridization of DNA sequences.
Gerasimova, Yulia V. +1 more
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Construction of a Fuzzy and Boolean Logic Gates Based on DNA
Small, 2015Logic gates are devices that can perform logical operations by transforming a set of inputs into a predictable single detectable output. The hybridization properties, structure, and function of nucleic acids can be used to make DNA-based logic gates. These devices are important modules in molecular computing and biosensing.
Reza M Zadegan +2 more
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Circular DNA Logic Gates with Strand Displacement
Langmuir, 2009Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring.
Cheng, Zhang, Jing, Yang, Jin, Xu
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DNA Sequential Logic Gate Using Two-Ring DNA
ACS Applied Materials & Interfaces, 2016Sequential DNA detection is a fundamental issue for elucidating the interactive relationships among complex gene systems. Here, a sequential logic DNA gate was achieved by utilizing the two-ring DNA structure, with the ability to recognize "before" and "after" triggering sequences of DNA signals.
Cheng, Zhang +5 more
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A DNA based molecular logic gate capable of a variety of logical operations
Natural Computing, 2013In this paper we report on a module in the RTRACS (Reverse-transcription and TRanscription-based Autonomous Computing System) molecular computing system, constructed with DNA, RNA and enzymes. The module is a 2-input logic gate that receives input and produces output in the form of RNA molecules.
Anton Kan +3 more
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