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Biocomputing: Beyond the Hype [PDF]
Journal of Medical Internet ResearchBiocomputing is a nascent but rapidly developing field at the intersection of biology and computer science.
Simon Spichak
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High-Performance Biocomputing in Synthetic Biology–Integrated Transcriptional and Metabolic Circuits
Frontiers in Bioengineering and Biotechnology, 2019 Biocomputing uses molecular biology parts as the hardware to implement computational devices. By following pre-defined rules, often hard-coded into biological systems, these devices are able to process inputs and return outputs—thus computing information.
Angel Goni-Moreno, Pablo I Nikel
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Bacterial gene regulatory neural network as a biocomputing library of mathematical solvers [PDF]
npj Systems Biology and ApplicationsCurrent biocomputing approaches predominantly rely on engineered circuits with fixed logic, offering limited stability and reliability under diverse environmental conditions.
Adrian Ratwatte +4 more
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Trumpet is an operating system for simple and robust cell-free biocomputing
Nature Communications, 2023 Biological computation is becoming a viable and fast-growing alternative to traditional electronic computing. Here we present a biocomputing technology called Trumpet: Transcriptional RNA Universal Multi-Purpose GatE PlaTform.
Judee A. Sharon +8 more
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Frontiers in Molecular Biosciences, 2022 The biological-biochemical community has been shocked and delighted by the remarkable progress that has recently been made on a problem that has consumed the attention, energy, and resources of many, if not most of the scientists in the field for the ...
Robert Schleif, Manuel Espinosa
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Large and stable: actin aster networks formed via entropic forces
Frontiers in Chemistry, 2022 Biopolymer networks play a major role as part of the cytoskeleton. They provide stable structures and act as a medium for signal transport. These features encourage the application of such networks as organic computation devices.
Friedrich Fabian Spukti +3 more
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PPDTS: Predicting potential drug–target interactions based on network similarity
IET Systems Biology, 2022 Identification of drug–target interactions (DTIs) has great practical importance in the drug discovery process for known diseases. However, only a small proportion of DTIs in these databases has been verified experimentally, and the computational methods
Wei Wang +5 more
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Biocomputing and Synthetic Biology in Cells: Cells Special Issue
Cells, 2020 Biocomputing and synthetic biology have been two of the most exciting emerging fields in recent years [...]
Feifei Cui, Quan Zou
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Cardiac Muscle Cell‐Based Coupled Oscillator Network for Collective Computing
Advanced Intelligent Systems, 2021 Current rate of data generation and the need for real‐time data analytics can benefit from new computational approaches where computation proceeds in a massively parallel way while being scalable and energy efficient.
Xiang Ren +8 more
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Evolutionary approach to construct robust codes for DNA-based data storage
Frontiers in Genetics, 2023 DNA is a practical storage medium with high density, durability, and capacity to accommodate exponentially growing data volumes. A DNA sequence structure is a biocomputing problem that requires satisfying bioconstraints to design robust sequences ...
Abdur Rasool +6 more
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