Results 21 to 30 of about 7,742 (179)
The essential component in DNA-based information storage system: robust error-tolerating module
Frontiers in Bioengineering and Biotechnology, 2014 The size of digital data is ever increasing and is expected to grow to 40,000EB by 2020, yet the estimated global information storage capacity in 2011 is less than 300EB, indicating that most of the data are transient. DNA, as a very stable nano-molecule,
Aldrin Kay-Yuen eYim +16 more
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Engineered microbial consortia: strategies and applications
Microbial Cell Factories, 2021 Many applications of microbial synthetic biology, such as metabolic engineering and biocomputing, are increasing in design complexity. Implementing complex tasks in single populations can be a challenge because large genetic circuits can be burdensome ...
Katherine E. Duncker +2 more
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Biomedicines, 2020 Enzymes are key proteins performing the basic functional activities in cells. In humans, enzymes can be also responsible for diseases, and the molecular mechanisms underlying the genotype to phenotype relationship are under investigation for diagnosis ...
Giulia Babbi +4 more
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Flavones scaffold of Chromolaena odorata as a potential xanthine oxidase inhibitor: Induced Fit Docking and ADME studies [PDF]
BioImpacts, 2020 Introduction: Gout is a type of painful inflammation initiated by the interactions between monosodium urate crystals and connective tissue. Xanthine oxidase (XO) catalyzes the oxidation of hypoxanthine to xanthine, then to uric acid.
Babatomiwa Kikiowo +8 more
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Cells, 2019 Enhancers are short deoxyribonucleic acid fragments that assume an important part in the genetic process of gene expression. Due to their possibly distant location relative to the gene that is acted upon, the identification of enhancers is difficult ...
Kok Keng Tan +3 more
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DeepEMhancer: a deep learning solution for cryo-EM volume post-processing
Communications Biology, 2021 Sanchez-Garcia et al. present DeepEMhancer, a deep learning-based method that can automatically perform post-processing of raw cryo-electron microscopy density maps.
Ruben Sanchez-Garcia +5 more
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Scientific Reports, 2017 Single Particle Analysis using cryo-electron microscopy is a structural biology technique aimed at capturing the three-dimensional (3D) conformation of biological macromolecules. Projection images used to construct the 3D density map are characterized by
J. Vargas +4 more
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Advanced Functional Materials, EarlyView.DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen +3 more
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Configuration‐Encoded Cell Alignment by Light‐Gated Silicon Photovoltaic Microcell Arrays
Advanced Functional Materials, EarlyView.Light‐gated silicon photovoltaic microcells convert pulsed illumination into localized electrical cues. Arranging otherwise similar microcells into four‐lobed, six‐lobed, or circular patterns directs fibroblasts into corresponding local arrangements without wired stimulation.
Yifan Tao +7 more
wiley +1 more source
Scientific Reports, 2022 According to databases such as OMIM, Humsavar, Clinvar and Monarch, 1494 human enzymes are presently associated to 2539 genetic diseases, 75% of which are rare (with an Orphanet code). The Mondo ontology initiative allows a standardization of the disease
Castrense Savojardo +4 more
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