Workflows for Rapid Functional Annotation of Diverse Arthropod Genomes
Insects, 2021 Genome sequencing of a diverse array of arthropod genomes is already underway, and these genomes will be used to study human health, agriculture, biodiversity, and ecology.
Surya Saha +4 more
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Functional Annotation Workflow for Fungal Transcriptomes [PDF]
Journal of FungiAlthough RNA sequencing (RNA-seq) enables rapid transcriptome profiling, functional annotation of fungal transcriptomes remains challenging. Existing tools prioritize broad taxonomic coverage, and reference genomes are scarce for non-model species.
Nagisa Morihara, Hidemasa Bono
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Artificial Intelligence Powers Protein Functional Annotation [PDF]
Advanced ScienceProtein functional annotation is essential for understanding biological processes, disease mechanisms, and enzyme activities, yet experimental validation remains costly and low‐throughput.
Wenkang Wang +4 more
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Evaluation of a hybrid approach using UBLAST and BLASTX for metagenomic sequences annotation of specific functional genes. [PDF]
PLoS ONE, 2014 The fast development of next generation sequencing (NGS) has dramatically increased the application of metagenomics in various aspects. Functional annotation is a major step in the metagenomics studies.
Ying Yang, Xiao-Tao Jiang, Tong Zhang
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Re-annotation is an essential step in systems biology modeling of functional genomics data. [PDF]
PLoS ONE, 2010 One motivation of systems biology research is to understand gene functions and interactions from functional genomics data such as that derived from microarrays.
Bart H J van den Berg +3 more
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Systematic Functional Annotation Workflow for Insects
Insects, 2022 Next-generation sequencing has revolutionized entomological study, rendering it possible to analyze the genomes and transcriptomes of non-model insects.
Hidemasa Bono +3 more
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Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources [PDF]
Frontiers in PharmacologyThe recent advancement of sequencing technologies marks a significant shift in the character and complexity of the digital genomic data universe, encompassing diverse types of molecular data, screened through manifold technological platforms. As a result,
Eleftherios Pilalis +7 more
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Student biocuration projects as a learning environment [version 2; peer review: 2 approved]
F1000Research, 2022 Background: Bioinformatics is becoming an essential tool for the majority of biological and biomedical researchers. Although bioinformatics data is exploited by academic and industrial researchers, limited focus is on teaching this area to undergraduates,
Ruth C. Lovering +2 more
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Capturing heart valve development with Gene Ontology
Frontiers in Genetics, 2023 Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed +4 more
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GOing Forward With the Cardiac Conduction System Using Gene Ontology
Frontiers in Genetics, 2022 The cardiac conduction system (CCS) comprises critical components responsible for the initiation, propagation, and coordination of the action potential. Aberrant CCS development can cause conduction abnormalities, including sick sinus syndrome, accessory
Kan Yan Chloe Li +3 more
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