Results 41 to 50 of about 361,695 (297)

Re‐annotation of the sequence > annotation: opportunities for the functional microbiologist [PDF]

Microbial Biotechnology, 2015
Functional annotation of proteins has been central to the development of biology in the post-genomic era. In such a way, the wealth of information encoded by genome sequences has become accessible to the broader biological community. One may even argue that this has served the purpose of democratization of science, as almost every scientist in the ...
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Non‐homology‐based prediction of gene functions in maize (Zea mays ssp. mays)

The Plant Genome, 2020
Advances in genome sequencing and annotation have eased the difficulty of identifying new gene sequences. Predicting the functions of these newly identified genes remains challenging.
Xiuru Dai, Zheng Xu, Zhikai Liang, Xiaoyu Tu, Silin Zhong, James C. Schnable, Pinghua Li   +6 more
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SFannotation: A Simple and Fast Protein Function Annotation System [PDF]

Genomics & Informatics, 2014
Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation ...
Dong Su Yu, Byung Kwon Kim
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Structural and functional annotation of the porcine immunome [PDF]

BMC Genomics, 2013
Abstract Background The domestic pig is known as an excellent model for human immunology and the two species share many pathogens. Susceptibility to infectious disease is one of the major constraints on swine performance, yet the structure and function of genes comprising the pig immunome are not well-characterized ...
Dawson, Harry D, Loveland, Jane E, Pascal, Géraldine, Gilbert, James G R, Uenishi, Hirohide, Mann, Katherine M, Sang, Yongming, Zhang, Jie, Carvalho-Silva, Denise, Hunt, Toby, Hardy, Matthew, Hu, Zhiliang, Zhao, Shu-Hong, Anselmo, Anna, Shinkai, Hiroki, Chen, Celine, Badaoui, Bouabid, Berman, Daniel, Amid, Clara, Kay, Mike, Lloyd, David, Snow, Catherine, Morozumi, Takeya, Cheng, Ryan Pei-Yen, Bystrom, Megan, Kapetanovic, Ronan, Schwartz, John C, Kataria, Ranjit, Astley, Matthew, Fritz, Eric, Steward, Charles, Thomas, Mark, Wilming, Laurens, Toki, Daisuke, Archibald, Alan L, Bed'Hom, Bertrand, Beraldi, Dario, Huang, Ting-Hua, Ait-Ali, Tahar, Blecha, Frank, Botti, Sara, Freeman, Tom C, Giuffra, Elisabetta, Hume, David A, Lunney, Joan K, Murtaugh, Michael P, Reecy, James M, Harrow, Jennifer L, Gaillard, Claire, Tuggle, Christopher K   +49 more
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Annotation extension through protein family annotation coherence metrics

Frontiers in Genetics, 2013
Protein functional annotation consists in associating proteins with textual descriptors elucidating their biological roles. The bulk of annotation is done via automated procedures that ultimately rely on annotation transfer.
Hugo Paulo Bastos, Luka Alexander Clarke, Francisco eCouto   +2 more
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AnnotaPipeline: An integrated tool to annotate eukaryotic proteins using multi-omics data

Frontiers in Genetics, 2022
Assignment of gene function has been a crucial, laborious, and time-consuming step in genomics. Due to a variety of sequencing platforms that generates increasing amounts of data, manual annotation is no longer feasible. Thus, the need for an integrated,
Guilherme Augusto Maia, Vilmar Benetti Filho, Eric Kazuo Kawagoe, Tatiany Aparecida Teixeira Soratto, Renato Simões Moreira, Renato Simões Moreira, Edmundo Carlos Grisard, Edmundo Carlos Grisard, Glauber Wagner, Glauber Wagner   +9 more
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Combining multiple functional annotation tools increases coverage of metabolic annotation

BMC Genomics, 2018
Background Genome-scale metabolic modeling is a cornerstone of systems biology analysis of microbial organisms and communities, yet these genome-scale modeling efforts are invariably based on incomplete functional annotations. Annotated genomes typically
Marc Griesemer, Jeffrey A. Kimbrel, Carol E. Zhou, Ali Navid, Patrik D’haeseleer   +4 more
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Functional annotation and ENU

BMC Research Notes, 2012
Abstract Functional annotation of every gene in the mouse genome is a herculean task that requires a multifaceted approach. Many large-scale initiatives are contributing to this undertaking. The International Knockout Mouse Consortium (IKMC) plans to mutate every protein-coding gene, using a combination of gene trapping and gene targeting in ...
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Functional annotation of hypothetical proteins – A review [PDF]

Bioinformation, 2006
The complete human genome sequences in the public database provide ways to understand the blue print of life. As of June 29, 2006, 27 archaeal, 326 bacterial and 21 eukaryotes is complete genomes are available and the sequencing for 316 bacterial, 24 archaeal, 126 eukaryotic genomes are in progress. The traditional biochemical/molecular experiments can
Selvarajan, Sivashankari, Piramanayagam, Shanmughavel   +1 more
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Metagenomic annotation networks: construction and applications. [PDF]

PLoS ONE, 2012
The derivation and comparison of biological interaction networks are vital for understanding the functional capacity and hierarchical organization of integrated microbial communities.
Gregory Vey, Gabriel Moreno-Hagelsieb
doaj   +1 more source