Results 61 to 70 of about 563,469 (347)

Assessing the performance of different approaches for functional and taxonomic annotation of metagenomes

BMC Genomics, 2019
Background Metagenomes can be analysed using different approaches and tools. One of the most important distinctions is the way to perform taxonomic and functional assignment, choosing between the use of assembly algorithms or the direct analysis of raw ...
Javier Tamames, Marta Cobo-Simón, Fernando Puente-Sánchez   +2 more
doaj   +1 more source

The impact of sequence database choice on metaproteomic results in gut microbiota studies [PDF]

, 2016
Background: Elucidating the role of gut microbiota in physiological and pathological processes has recently emerged as a key research aim in life sciences.
Addis, Maria Filippa, Deligios, Massimo, Fraumene, Cristina, Manghina, Valeria, Martens, Lennart, Muth, Thilo, Pagnozzi, Daniela, Palomba, Antonio, Rapp, Erdmann, Tanca, Alessandro, Uzzau, Sergio   +10 more
core   +4 more sources

Protein family classification and functional annotation [PDF]

Computational Biology and Chemistry, 2003
With the accelerated accumulation of genomic sequence data, there is a pressing need to develop computational methods and advanced bioinformatics infrastructure for reliable and large-scale protein annotation and biological knowledge discovery. The Protein Information Resource (PIR) provides an integrated public resource of protein informatics to ...
Cathy H, Wu, Hongzhan, Huang, Lai-Su L, Yeh, Winona C, Barker   +3 more
openaire   +2 more sources

Representation of non-coding RNA-mediated regulation of gene expression using the Gene Ontology

RNA Biology
Regulatory non-coding RNAs (ncRNAs) are increasingly recognized as integral to the control of biological processes. This is often through the targeted regulation of mRNA expression, but this is by no means the only mechanism through which regulatory ...
Giulia Antonazzo, Pascale Gaudet, Ruth C. Lovering, Helen Attrill   +3 more
doaj   +1 more source

Assessment of genome annotation using gene function similarity within the gene neighborhood

BMC Bioinformatics, 2017
Background Functional annotation of bacterial genomes is an obligatory and crucially important step of information processing from the genome sequences into cellular mechanisms. However, there is a lack of computational methods to evaluate the quality of
Se-Ran Jun, Intawat Nookaew, Loren Hauser, Andrey Gorin   +3 more
doaj   +1 more source

Functional Annotation Analytics of Genomes

Bioinformatics and Biology Insights, 2011
Rhodopseudomonas palustris , a nonsulphur purple photosynthetic bacteria, has been extensively investigated for its metabolic versatility including ability to produce hydrogen gas from sunlight and biomass.
Shaneka S. Simmons, Raphael D. Isokpehi, Shyretha D. Brown, Donee L. Mcallister, Charnia C. Hall, Wanaki M. Mcduffy, Tamara L. Medley, Udensi K. Udensi, Rajendram V. Rajnarayanan, Wellington K. Ayensu, Hari H.P. Cohly   +10 more
doaj   +1 more source

Parsing Arabic using treebank-based LFG resources [PDF]

, 2009
In this paper we present initial results on parsing Arabic using treebank-based parsers and automatic LFG f-structure annotation methodologies. The Arabic Annotation Algorithm (A3) (Tounsi et al., 2009) exploits the rich functional annotations in the ...
Attia, Mohammed, Tounsi, Lamia, van Genabith, Josef   +2 more
core  

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

ProFAB—open protein functional annotation benchmark

Briefings in Bioinformatics, 2023
AbstractAs the number of protein sequences increases in biological databases, computational methods are required to provide accurate functional annotation with high coverage. Although several machine learning methods have been proposed for this purpose, there are still two main issues: (i) construction of reliable positive and negative training and ...
A Samet Özdilek, Ahmet Atakan, Gökhan Özsarı, Aybar Acar, M Volkan Atalay, Tunca Doğan, Ahmet S Rifaioğlu   +6 more
openaire   +3 more sources

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers, Chantal Éthier, Caroline Laverdière, Nathalie Alos, Thai Hoa Tran, Marie‐Claude Pelland‐Marcotte   +5 more
wiley   +1 more source