Results 71 to 80 of about 361,695 (297)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

FAVOR: functional annotation of variants online resource and annotator for variation across the human genome

, 2023
Large biobank-scale whole genome sequencing (WGS) studies are rapidly identifying a multitude of coding and non-coding variants. They provide an unprecedented resource for illuminating the genetic basis of human diseases.
Matise, Tara, Rehm, Heidi L., Cox, Nancy, Felsenfeld, Adam, Blue, Elizabeth E., Li, Zilin, Zheng, Xiuwen, Buyske, Steven, Sofia, Heidi J., Li, Xihao, Moore, Jill, Kenny, Eimear, NHGRI Genome Sequencing Program Variant Functional Annotation Working Group, Asok, Abhijith, Gerstein, Mark, Weng, Zhiping, Neale, Benjamin, Sunyaev, Shamil R., Philippakis, Anthony, Snyder, Grace, Zhou, Hufeng, Li, Bingshan, Arapoglou, Theodore, Lin, Xihong, Kumar, Sushant   +24 more
core   +1 more source

Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana

, 2007
We present here the annotation of the complete genome of rice Oryza sativa L. ssp. japonica cultivar Nipponbare. All functional annotations for proteins and non-protein-coding RNA (npRNA) candidates were manually curated.
Hosokawa, S., Kawashima, H., Zhao, Q., Kawahara, Y., Zhao, Q., Imanishi, T., Haberer, G., Seki, M., Komatsu, S., Thongjuea, S., Oota, S., Wang, A., Takeda, J.-i., Bureau, T., Ikawa, H., Hokari, H., Zhang, H., Schoof, H., Yamamoto, N., Khurana, J.P., Tanaka, T., Tanino, M., Thongjuea, S., Sakai, Y., Ito, Y., Tanaka, T., Kawamura, T., Antonio, B. A., Harada, E., Messing, J., Saichi, N., Fuks, G., Hirochika, H., Koyanagi, K. O., Sato, Y., Sakai, H., Tyagi, A. K., Bureau, T., Kawamura, T., Aono, H., Ohyanagi, H., Burr, B., Barrero, R.A., Okido, T., Tsugane, M., Shimizu, Y., Osato, N., Hilton, P.B., Wang, A., Yu, Y., Hoen, D., Matsuya, A., Barrero, R. A., Bruskiewich, R., Nam, J., Apweiler, R., Shibata, M., Miyao, A., Miyao, A., Schoof, H., Fujii, Y., Quetier, F., Lieberherr, D., Nurimoto, S., Burr, B., Hiraki, A.T., Sakai, H., Tatusova, T., Hoen, D., Sakata, K., Sato, F., Lin, Y. C., Sakurai, T., Higo, K., Lonsdale, D., Nurimoto, S., Hiraki, A. T., Habara, T., Shimizu, Y., Ito, Y., Lin, Y-C, Tsugane, M., McCombie, W. R., Okido, T., Namiki, N., Kawahara, Y., Apweiler, R., Mulder, N., Kawashima, H., Matsumoto, T., Quetier, F., Osato, N., Hsing, Y., Hilton, P. B., Shinso, Y., Aono, H., Ohyanagi, H., Yamasaki, C., Sakai, Y., Yamaguchi, K., Vanavichit, A., Kubooka, H., O'Donovan, C., Komatsu, S., Matsuya, A., Fuks, G., Lieberherr, D., Antonio, B.A., Yamamoto, N., OOta, S., Hokari, H., Sakata, K., Raghuvanshi, S., Jaiswal, P., Burr, F., Hsing, Y. I., Smith-White, B., Khurana, J. P., O'Donovan, C., Vanavichit, A., De Oliveira, A. C., Habara, T., Ikawa, H., Shibata, M., Bruskiewich, R., Koyanagi, K.O., Gojobori, T., Harada, E., Raghuvanshi, S., Hosokawa, S., Sato, F., Seki, M., Higo, K., Yamamoto, M., Palmer, L.E., Kubooka, H., Kikuchi, S., Sasaki, T., Yu, Y., Han, B., Nam, J., Costa de Oliveira, A., Palmer, L. E., Lonsdale, D., McCombie, W.R., Shinso, Y., Kanno, M., Tatusova, T., Yamasaki, C., Haberer, G., Numa, H., Yamaguchi, K., Hirochika, H., Ikeo, K., Ikeo, K., Todokoro, F., Burr, F., Zhang, H., Singh, N. K., Kanno, M., Smith-White, B., Wing, R.A., Sato, Y., Nagamura, Y., Wing, R. A., Fujii, Y., Jaiswal, P., Messing, J., Kikuchi, S., Saichi, N., Namiki, N., Tyagi, A.K., Itoh, T., Tanino, M., Itoh, T., Imanishi, T., Sakurai, T., Todokoro, F., Mulder, N., Matsumoto, T., Singh, N.K., Nagamura, Y., Yamamoto, M., Shinozaki, K., Takeda, J. I., Han, B., Sasaki, T., Numa, H., Shinozaki, K., Gojobori, T.   +189 more
core   +1 more source

Functional annotation for 15 diverse arthropod genomes

, 2021
We present the annotation results of 15 arthropod proteomes using an open source, open access and containerized pipeline for genome-scale functional annotation of insect proteomes and apply it to a diverse range of arthropod species.
Anna K. Childers (17483073), Monica F. Poelchau (17483076), Fiona M. McCarthy (17483079), Surya Saha (17477823), Amanda M. Cooksey (17483070)   +4 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

EuCAP, a Eukaryotic Community Annotation Package, and its application to the rice genome

BMC Genomics, 2007
Background Despite the improvements of tools for automated annotation of genome sequences, manual curation at the structural and functional level can provide an increased level of refinement to genome annotation.
Hamilton John P, Campbell Matthew, Thibaud-Nissen Françoise, Zhu Wei, Buell C   +4 more
doaj   +1 more source

Fungal genomes: suffering with functional annotation errors

IMA Fungus, 2021
Background The genome sequence data of more than 65985 species are publicly available as of October 2021 within the National Center for Biotechnology Information (NCBI) database alone and additional genome sequences are available in other databases and ...
Tapan Kumar Mohanta, Ahmed Al-Harrasi
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

OntoTag - A Linguistic and Ontological Annotation Model Suitable for the Semantic Web

, 2012
OntoTag - A Linguistic and Ontological Annotation Model Suitable for the Semantic Web 1. INTRODUCTION. LINGUISTIC TOOLS AND ANNOTATIONS: THEIR LIGHTS AND SHADOWS Computational Linguistics is already a consolidated research area.
Pareja-Lora, A.
core   +1 more source