Results 31 to 40 of about 339,629 (251)

Phylogenetic molecular function annotation

Journal of Physics: Conference Series, 2009
It is now easier to discover thousands of protein sequences in a new microbial genome than it is to biochemically characterize the specific activity of a single protein of unknown function. The molecular functions of protein sequences have typically been predicted using homology-based computational methods, which rely on the principle that homologous ...
Barbara E, Engelhardt, Michael I, Jordan, Susanna T, Repo, Steven E, Brenner   +3 more
openaire   +2 more sources

The first draft genome assembly and data analysis of the Malaysian mahseer (Tor tambroides)

Aquaculture and Fisheries, 2023
The Malaysian mahseer (Tor tambroides), one of the most valuable freshwater fish in the world, is mainly targeted for human consumption. The mitogenomic data of this species is available to date, but the genomic information is still lacking.
Melinda Mei Lin Lau, Leonard Whye Kit Lim, Hung Hui Chung, Han Ming Gan   +3 more
doaj   +1 more source

SFannotation: A Simple and Fast Protein Function Annotation System [PDF]

Genomics & Informatics, 2014
Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation ...
Dong Su Yu, Byung Kwon Kim
doaj   +1 more source

Non‐homology‐based prediction of gene functions in maize (Zea mays ssp. mays)

The Plant Genome, 2020
Advances in genome sequencing and annotation have eased the difficulty of identifying new gene sequences. Predicting the functions of these newly identified genes remains challenging.
Xiuru Dai, Zheng Xu, Zhikai Liang, Xiaoyu Tu, Silin Zhong, James C. Schnable, Pinghua Li   +6 more
doaj   +1 more source

Functional annotation of hypothetical proteins – A review [PDF]

Bioinformation, 2006
The complete human genome sequences in the public database provide ways to understand the blue print of life. As of June 29, 2006, 27 archaeal, 326 bacterial and 21 eukaryotes is complete genomes are available and the sequencing for 316 bacterial, 24 archaeal, 126 eukaryotic genomes are in progress. The traditional biochemical/molecular experiments can
Selvarajan, Sivashankari, Piramanayagam, Shanmughavel   +1 more
openaire   +2 more sources

Combining multiple functional annotation tools increases coverage of metabolic annotation

BMC Genomics, 2018
Background Genome-scale metabolic modeling is a cornerstone of systems biology analysis of microbial organisms and communities, yet these genome-scale modeling efforts are invariably based on incomplete functional annotations. Annotated genomes typically
Marc Griesemer, Jeffrey A. Kimbrel, Carol E. Zhou, Ali Navid, Patrik D’haeseleer   +4 more
doaj   +1 more source

AnnotaPipeline: An integrated tool to annotate eukaryotic proteins using multi-omics data

Frontiers in Genetics, 2022
Assignment of gene function has been a crucial, laborious, and time-consuming step in genomics. Due to a variety of sequencing platforms that generates increasing amounts of data, manual annotation is no longer feasible. Thus, the need for an integrated,
Guilherme Augusto Maia, Vilmar Benetti Filho, Eric Kazuo Kawagoe, Tatiany Aparecida Teixeira Soratto, Renato Simões Moreira, Renato Simões Moreira, Edmundo Carlos Grisard, Edmundo Carlos Grisard, Glauber Wagner, Glauber Wagner   +9 more
doaj   +1 more source

Annotation extension through protein family annotation coherence metrics

Frontiers in Genetics, 2013
Protein functional annotation consists in associating proteins with textual descriptors elucidating their biological roles. The bulk of annotation is done via automated procedures that ultimately rely on annotation transfer.
Hugo Paulo Bastos, Luka Alexander Clarke, Francisco eCouto   +2 more
doaj   +1 more source

Revisiting the functional annotation of TriTryp using sequence similarity tools [PDF]

Heliyon
Reza Salavati, Poorya Mirzavand Borujeni   +1 more
exaly   +2 more sources

Functional annotation and ENU

BMC Research Notes, 2012
Abstract Functional annotation of every gene in the mouse genome is a herculean task that requires a multifaceted approach. Many large-scale initiatives are contributing to this undertaking. The International Knockout Mouse Consortium (IKMC) plans to mutate every protein-coding gene, using a combination of gene trapping and gene targeting in ...
openaire   +2 more sources