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Capturing heart valve development with Gene Ontology
Frontiers in Genetics, 2023 Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed +4 more
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GOing Forward With the Cardiac Conduction System Using Gene Ontology
Frontiers in Genetics, 2022 The cardiac conduction system (CCS) comprises critical components responsible for the initiation, propagation, and coordination of the action potential. Aberrant CCS development can cause conduction abnormalities, including sick sinus syndrome, accessory
Kan Yan Chloe Li +3 more
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Insights into Online microRNA Bioinformatics Tools
Non-Coding RNA, 2023 MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes.
Diana Luna Buitrago +2 more
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XACML Function Annotations [PDF]
Eighth IEEE International Workshop on Policies for Distributed Systems and Networks (POLICY'07), 2007 XACML is being increasingly adopted in large enterprise systems for specifying access control policies. However, the efficient analysis and integration of multiple policies in such large distributed systems still remains a difficult task. In this paper, we propose an annotation technique which is a simple extension to XACML, and may greatly benefit the
Rao, Prathima, Lin, Dan, Bertino, Elisa
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Prediction of Metabolic Pathways Involvement in Prokaryotic UniProtKB Data by Association Rule Mining [PDF]
, 2016 The widening gap between known proteins and their functions has encouraged the development of methods to automatically infer annotations. Automatic functional annotation of proteins is expected to meet the conflicting requirements of maximizing ...
Boudellioua, Imane +4 more
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BMC Genomics, 2021 Background Functional genome annotation is the process of labelling functional genomic regions with descriptive information. Manual curation can produce higher quality genome annotations than fully automated methods.
Matthew R. Lueder +6 more
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Workflows for Rapid Functional Annotation of Diverse Arthropod Genomes
Insects, 2021 Genome sequencing of a diverse array of arthropod genomes is already underway, and these genomes will be used to study human health, agriculture, biodiversity, and ecology.
Surya Saha +4 more
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Evaluation of a hybrid approach using UBLAST and BLASTX for metagenomic sequences annotation of specific functional genes. [PDF]
PLoS ONE, 2014 The fast development of next generation sequencing (NGS) has dramatically increased the application of metagenomics in various aspects. Functional annotation is a major step in the metagenomics studies.
Ying Yang, Xiao-Tao Jiang, Tong Zhang
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Functional annotation of regulatory pathways [PDF]
Bioinformatics, 2007 Abstract Motivation: Standardized annotations of biomolecules in interaction networks (e.g. Gene Ontology) provide comprehensive understanding of the function of individual molecules. Extending such annotations to pathways is a critical component of functional characterization of cellular signaling at the systems level ...
Jayesh, Pandey +5 more
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PINOT: an intuitive resource for integrating protein-protein interactions
Cell Communication and Signaling, 2020 Background The past decade has seen the rise of omics data for the understanding of biological systems in health and disease. This wealth of information includes protein-protein interaction (PPI) data derived from both low- and high-throughput assays ...
James E. Tomkins +7 more
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