Results 151 to 160 of about 2,686,549 (398)
Molecular Analysis of N6-Methyladenine Patterns in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e Nuclear DNA [PDF]
, 1989 We have cloned two DNA fragments containing 5\u27-GATC-3\u27 sites at which the adenine is methylated in the macronucleus of the ciliate Tetrahymena thermophila. Using these cloned fragments as molecular probes, we analyzed the maintenance of methylation
Capowski, Elizabeth E. +3 more
core +1 more source
Global increase in DNA methylation during orange fruit development and ripening
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance A global loss of DNA methylation due to active DNA demethylation is critical to the regulation of tomato fruit ripening. It is unclear whether and how DNA methylation may change during the ripening of other fruits. We found a global increase
Huan‐Wei Huang +8 more
semanticscholar +1 more source
Postępy Higieny i Medycyny Doświadczalnej, 2014 The number of overweight and obese people is increasing at an alarming rate, especially in the developed and developing countries. Obesity is a major risk factor for diabetes, cardiovascular disease, and cancer, and in consequence for premature death. The development of obesity results from the interplay of both genetic and environmental factors, which
Iwona Wybrańska +3 more
openaire +3 more sources
Advanced Biology, EarlyView.The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez +8 more
wiley +1 more source
Cell Reports, 2017 Summary: DNA methylation plays crucial roles in chromatin structure and gene expression. Aberrant DNA methylation patterns, including global hypomethylation and regional hypermethylation, are associated with cancer and implicated in oncogenic events. How
Nicolas Veland +8 more
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Advanced Engineering Materials, EarlyView.Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
DNA methylation at a CCGG sequence in the large intron of the rabbit β-globin gene: tissue-specific variations [PDF]
, 1978 Cees Waalwijk, Richard A. Flavell
openalex +1 more source
Epigenetics & Chromatin, 2018 DNA methylation is one of the main epigenetic mechanisms for the regulation of gene expression in eukaryotes. In the standard model, methylation in gene promoters has received the most attention since it is generally associated with transcriptional ...
Dafni Anastasiadi +2 more
semanticscholar +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Repair methylation of parental DNA In synchronized cultures of Novikoff hepatoma cells [PDF]
, 1975 Julia K. Hilliard, Thomas W. Sneider
openalex +1 more source