Results 181 to 190 of about 551,287 (374)
Advanced Science, EarlyView.This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran +7 more
wiley +1 more source
Birth defects associated with paternal firefighting in the National Birth Defects Prevention Study
American Journal of Industrial Medicine, Volume 66, Issue 1, Page 30-40, January 2023., 2023 Abstract Background Few studies have evaluated birth defects among children of firefighters. We investigated associations between birth defects and paternal work as a firefighter compared to work in non‐firefighting and police officer occupations. Methods We analyzed 1997–2011 data from the multi‐site case‐control National Birth Defects Prevention ...
Miriam R. Siegel +7 more
wiley +1 more source
Kinetics of Methylation of DNA by a Restriction Endonuclease from Escherichia coli B
, 1974 Gerald F. Vovis +2 more
openalex +1 more source
Advanced Science, EarlyView.Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang +12 more
wiley +1 more source
Tissue mosaicism, FMR1 expression and intellectual functioning in males with fragile X syndrome
American Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 357-369, February 2023., 2023 Abstract Fragile X syndrome (FXS) is caused by hypermethylation of the FMR1 promoter due to the full mutation expansion (full mutation [FM]: CGG ≥ 200 repeats) and silencing of FMR1. Assessment of mosaicism for active‐unmethylated alleles has prognostic utility.
Emma K. Baker +17 more
wiley +1 more source
Advanced Science, EarlyView.Early detection of hepatocellular carcinoma in patients with liver cirrhosis and/or hepatitis virus B/C infection improves survival. Through marker discovery, 8 methylated DNA markers are identified and a logistic regression model (COMET‐LR) is built in the training set, which achieved 90.0% sensitivity at 97.4% specificity in the validation set.
Tian Yang +16 more
wiley +1 more source
Inheritance of DNA methylation in Coprinus cinereus. [PDF]
, 1986 Miriam E. Zolan, Patricia J. Pukkila
openalex +1 more source