Results 181 to 190 of about 2,686,549 (398)

Sequence organisation in nuclear DNA from Physarum polycephalum: methylation of repetitive sequences [PDF]

, 1981
Paul A. Whittaker, A. McLachlan, Norman Hardman   +2 more
openalex   +1 more source

Navigating the DNA methylation landscape of cancer.

Trends in Genetics, 2021
Atsuya Nishiyama, M. Nakanishi
semanticscholar   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

Perturbation of maintenance and de novo DNA methylation in vitro by UVB (280-340 nm)-induced pyrimidine photodimers. [PDF]

, 1985
Frederick F. Becker, Pamela Holton, Mathuros Ruchirawat, J Lapeyre   +3 more
openalex   +1 more source

DNA Synthesis, Methylation and Degradation During Conjugation in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]

, 1985
We have investigated the timing of DNA synthesis, methylation and degradation during macronuclear development in the ciliate, Tetrahymena thermophila. DNA synthesis was first detected in the anlagen early in macronuclear development, but the majority of ...
Harrison, Gail Singer, Karrer, Kathleen M.   +1 more
core   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

DNA methylation and viral gene expression in adenovirus-transformed and-infected cells [PDF]

, 1980
Lily Vardimon, Rainer Neumann, Ingrid Kuhlmann, Diane Sutter, Walter Doerfler   +4 more
openalex   +1 more source

Tumor induction by disruption of the Dnmt1, PCNA and UHRF1 interactions. [PDF]

, 2008
The low level of DNA methylation in tumors compared to the level of DNA methylation in their normal-tissue counterparts or global DNA hypomethylation was one of the first epigenetic alterations to be found in human cancer^1,2^.
Audrey Geairon, Emilie Debien, Eric Hervouet, Francois Vallette, Helene Rogniaux, Lisenn Lalier, Mathilde Cheray, Pierre-Francois Cartron   +7 more
core   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

In vitro methylation of DNA with Hpa II methylase [PDF]

, 1981
Adinah Quint, Howard Cedar
openalex   +1 more source