Results 1 to 10 of about 229,327 (196)

DNA microarray chip assay in new use: early diagnostic value in cutaneous mycobacterial infection [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionThe clinical practicability of DNA microarray chip in detecting the presence of mycobacterial species/isolates directly in the skin tissues has not been evaluated, nor the efficacy of DNA microarray chip as a novel diagnostic tool for the ...
Qian Yu   +6 more
doaj   +2 more sources

Progress in the Application of DNA Microarrays [PDF]

open access: diamondEnvironmental Health Perspectives, 2001
Microarray technology has been applied to a variety of different fields to address fundamental research questions. The use of microarrays, or DNA chips, to study the gene expression profiles of biologic samples began in 1995. Since that time, the fundamental concepts behind the chip, the technology required for making and using these chips, and the ...
Edward K. Lobenhofer   +3 more
openalex   +5 more sources

Normalizing DNA Microarray Data [PDF]

open access: goldCurrent Issues in Molecular Biology, 2002
DNA microarrays are a powerful tool to investigate differential gene expression for thousands of genes simultaneously. Although DNA microarrays have been widely used to understand the critical events underlying growth, development, homeostasis, behavior and the onset of disease, the management of the resulting data has received little attention ...
Martin Bilban   +4 more
openalex   +3 more sources

DNA/DNA microarrays [PDF]

open access: bronzeGenome Biology, 2001
Jonathan B Weitzman
openalex   +3 more sources

Diversity of the bovine genes IRAK1 and IRAK4 in the Toll-like receptor signaling pathway

open access: yesCzech Journal of Animal Science, 2023
Innate immunity is the organism's first line of defence, and the receptors of immune cells play a key role. Interleukin 1 receptor-associated kinase 1 and 4 (IRAK1 and IRAK4) are necessary for signal transmission from Toll-like receptors, which are the ...
Ladislav Tichý   +5 more
doaj   +1 more source

Hypertension-Associated Genes in the Mesenteric Artery of Three Spontaneously Hypertensive Rat Substrains Identified Using a DNA Array Method

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: Although the mesenteric artery plays a key role in regulating peripheral blood pressure, the molecular mechanisms that underlie the development of essential hypertension are not yet fully understood.
Yoshinori Aragane   +4 more
doaj   +1 more source

Long-Term Oral Administration of LLHK, LHK, and HK Alters Gene Expression Profile and Restores Age-Dependent Atrophy and Dysfunction of Rat Salivary Glands

open access: yesBiomedicines, 2020
Xerostomia, also known as dry mouth, is caused by a reduction in salivary secretion and by changes in the composition of saliva associated with the malfunction of salivary glands. Xerostomia decreases quality of life.
Yasuko Ishikawa   +6 more
doaj   +1 more source

Prospects of DNA microarray application in management of chronic obstructive pulmonary disease: A systematic review

open access: yesFrigid Zone Medicine, 2023
Chronic obstructive pulmonary disease (COPD) is incurable chronic disease which kills 3.3 million each year worldwide. Number of global cases of COPD is steadily rising alongside with life expectancy, disproportionally hitting middle-income countries ...
Anastasiia Litvinova, Ilia Bykov
doaj   +1 more source

DNA microarrays and development [PDF]

open access: yesHuman Molecular Genetics, 2003
Gene expression is a central concept in molecular biology: its control, frequently exquisite in terms of cell specificity and timing, forms part of our explanation of most biological processes. The importance of the control of gene expression for developmental biologists is made obvious by just considering the nature of their discipline. Development is
Andy Greenfield, Lee B. Smith
openaire   +3 more sources

DNA Microarrays for Identifying Fishes [PDF]

open access: yesMarine Biotechnology, 2008
In many cases marine organisms and especially their diverse developmental stages are difficult to identify by morphological characters. DNA-based identification methods offer an analytically powerful addition or even an alternative. In this study, a DNA microarray has been developed to be able to investigate its potential as a tool for the ...
M. Kochzius   +17 more
openaire   +3 more sources

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