Results 1 to 10 of about 3,572 (90)

Diversity of the bovine genes IRAK1 and IRAK4 in the Toll-like receptor signaling pathway

Czech Journal of Animal Science, 2023
Innate immunity is the organism's first line of defence, and the receptors of immune cells play a key role. Interleukin 1 receptor-associated kinase 1 and 4 (IRAK1 and IRAK4) are necessary for signal transmission from Toll-like receptors, which are the ...
Ladislav Tichý, Karel Novák, Jitka Kyselová, Michaela Přibáňová, Jan Calta, Luboš Vostrý   +5 more
doaj   +1 more source

Hypertension-Associated Genes in the Mesenteric Artery of Three Spontaneously Hypertensive Rat Substrains Identified Using a DNA Array Method

Frontiers in Bioscience-Landmark, 2022
Background: Although the mesenteric artery plays a key role in regulating peripheral blood pressure, the molecular mechanisms that underlie the development of essential hypertension are not yet fully understood.
Yoshinori Aragane, Toshihide Higashino, Kosho Kinoshita, Mohammad Said Ashenagar, Hideaki Higashino   +4 more
doaj   +1 more source

Prospects of DNA microarray application in management of chronic obstructive pulmonary disease: A systematic review

Frigid Zone Medicine, 2023
Chronic obstructive pulmonary disease (COPD) is incurable chronic disease which kills 3.3 million each year worldwide. Number of global cases of COPD is steadily rising alongside with life expectancy, disproportionally hitting middle-income countries ...
Anastasiia Litvinova, Ilia Bykov
doaj   +1 more source

Long-Term Oral Administration of LLHK, LHK, and HK Alters Gene Expression Profile and Restores Age-Dependent Atrophy and Dysfunction of Rat Salivary Glands

Biomedicines, 2020
Xerostomia, also known as dry mouth, is caused by a reduction in salivary secretion and by changes in the composition of saliva associated with the malfunction of salivary glands. Xerostomia decreases quality of life.
Yasuko Ishikawa, Tomasz D Pieczonka, Aneta M Bragiel-Pieczonka, Harumichi Seta, Tadahiro Ohkuri, Yumi Sasanuma, Yuji Nonaka   +6 more
doaj   +1 more source

DNA microarray chip assay in new use: early diagnostic value in cutaneous mycobacterial infection

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionThe clinical practicability of DNA microarray chip in detecting the presence of mycobacterial species/isolates directly in the skin tissues has not been evaluated, nor the efficacy of DNA microarray chip as a novel diagnostic tool for the ...
Qian Yu, Yuanyuan Wang, Zhiqin Gao, Hong Yang, Siyu Liu, Jingwen Tan, Lianjuan Yang   +6 more
doaj   +1 more source

Direct Detection of Drug-Resistant Hepatitis B Virus in Serum Using a Dendron-Modified Microarray

Gut and Liver, 2018
Background/AimsDirect sequencing is the gold standard for the detection of drug-resistance mutations in hepatitis B virus (HBV); however, this procedure is time-consuming, labor-intensive, and difficult to adapt to high-throughput screening.
Doo Hyun Kim, Hong Seok Kang, Seong-Suk Hur, Seobo Sim, Sung Hyun Ahn, Yong Kwang Park, Eun-Sook Park, Ah Ram Lee, Soree Park, So Young Kwon, Jeong-Hoon Lee, Kyun-Hwan Kim   +11 more
doaj   +1 more source

Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae. [PDF]

PLoS Neglected Tropical Diseases, 2008
The use of DNA microarray technology to study global Schistosoma gene expression has led to the rapid identification of novel biological processes, pathways or associations.
Jennifer M Fitzpatrick, Anna V Protasio, Andrew J McArdle, Gary A Williams, David A Johnston, Karl F Hoffmann   +5 more
doaj   +1 more source

PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas

OncoImmunology, 2017
Soft-tissue sarcomas (STS) are a group of rare, heterogeneous, and aggressive tumors, with high metastatic risk and relatively few efficient systemic therapies.
François Bertucci, Pascal Finetti, Delphine Perrot, Agnès Leroux, Françoise Collin, Axel Le Cesne, Jean-Michel Coindre, Jean-Yves Blay, Daniel Birnbaum, Emilie Mamessier   +9 more
doaj   +1 more source

Comprehensive Analysis of Prokaryotes in Environmental Water Using DNA Microarray Analysis and Whole Genome Amplification

Pathogens, 2013
The microflora in environmental water consists of a high density and diversity of bacterial species that form the foundation of the water ecosystem. Because the majority of these species cannot be cultured in vitro, a different approach is needed to ...
Norihisa Ishii, Noboru Fujitani, Akihisa Hata, Yuqian Luo, Yuko Ishido, Moyuru Hayashi, Kazunari Tanigawa, Akira Kawashima, Takeshi Akama, Koichi Suzuki   +9 more
doaj   +1 more source

Diffuse astrocytoma with 3q26.2q29 duplication, 20p12.1p11.1 deletion and no recurrence over 25 years

Interdisciplinary Neurosurgery, 2020
Background: The natural history of diffuse astrocytomas is thought to have a median time to malignant progression of 4–5 years. Nonetheless, the genetic changes in non-progressive tumors is still being established. Case description: We describe a 22 year
Mahlon D. Johnson, M. Anwar Iqbal, Ali Hussain, Webster Pilcher   +3 more
doaj   +1 more source