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DNA microarray chip assay in new use: early diagnostic value in cutaneous mycobacterial infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionThe clinical practicability of DNA microarray chip in detecting the presence of mycobacterial species/isolates directly in the skin tissues has not been evaluated, nor the efficacy of DNA microarray chip as a novel diagnostic tool for the ...
Qian Yu +6 more
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The effects of mismatches on hybridization in DNA microarrays: determination of nearest neighbor parameters [PDF]
Nucleic Acid Research 37, e53 (2009), 2010 Quantifying interactions in DNA microarrays is of central importance for a better understanding of their functioning. Hybridization thermodynamics for nucleic acid strands in aqueous solution can be described by the so-called nearest-neighbor model ...
Bloomfield +23 more
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Application of new probabilistic graphical models in the genetic regulatory networks studies [PDF]
J Biomed Inform. 2005 Dec;38(6):443-55. Epub 2005 Jun 9, 2005 This paper introduces two new probabilistic graphical models for reconstruction of genetic regulatory networks using DNA microarray data. One is an Independence Graph (IG) model with either a forward or a backward search algorithm and the other one is a ...
Anderson +37 more
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Limit Theorems for Hybridization Reactions on Oligonucleotide Microarrays [PDF]
arXiv, 2008 We derive herein the limiting laws for certain stationary distributions of birth-and-death processes related to the classical model of chemical adsorption-desorption reactions due to Langmuir.
Pawlikowska, Iwona, Rempala, Grzegorz A.
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Compressive Sensing DNA Microarrays [PDF]
EURASIP Journal on Bioinformatics and Systems Biology, 2008 Compressive sensing microarrays (CSMs) are DNA-based sensors that operate using group testing and compressive sensing (CS) principles. In contrast to conventional DNA microarrays, in which each genetic sensor is designed to respond to a single target, in
Baraniuk, RG +3 more
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On Limits of Performance of DNA Microarrays [PDF]
2006 IEEE International Conference on Acoustics Speed and Signal Processing Proceedings, 2006 DNA microarray technology relies on the hybridization process which is stochastic in nature. Probabilistic cross-hybridization of non-specific targets, as well as the shot-noise originating from specific targets binding, are among the many obstacles for ...
Hassibi, A., Hassibi, B., Vikalo, H.
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A digital microarray using interferometric detection of plasmonic nanorod labels [PDF]
arXiv, 2018 DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species. The mediocre sensitivity and dynamic range of traditional fluorescence microarrays compared to
Daaboul, George +3 more
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Thermodynamic behavior of short oligonucleotides in microarray hybridizations can be described using Gibbs free energy in a nearest-neighbor model [PDF]
J. Phys. Chem. B 111, 13583 (2007), 2007 While designing oligonucleotide-based microarrays, cross-hybridization between surface-bound oligos and non-intended labeled targets is probably the most difficult parameter to predict. Although literature describes rules-of-thumb concerning oligo length,
Carlon, E. +3 more
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Diversity of the bovine genes IRAK1 and IRAK4 in the Toll-like receptor signaling pathway
Czech Journal of Animal Science, 2023 Innate immunity is the organism's first line of defence, and the receptors of immune cells play a key role. Interleukin 1 receptor-associated kinase 1 and 4 (IRAK1 and IRAK4) are necessary for signal transmission from Toll-like receptors, which are the ...
Ladislav Tichý +5 more
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Frontiers in Bioscience-Landmark, 2022 Background: Although the mesenteric artery plays a key role in regulating peripheral blood pressure, the molecular mechanisms that underlie the development of essential hypertension are not yet fully understood.
Yoshinori Aragane +4 more
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