Results 21 to 30 of about 29,814 (210)

Effect of DNA Origami Nanostructures on hIAPP Aggregation

open access: yesNanomaterials, 2020
The aggregation of human islet amyloid polypeptide (hIAPP) plays a major role in the pathogenesis of type 2 diabetes mellitus (T2DM), and numerous strategies for controlling hIAPP aggregation have been investigated so far.
Marcel Hanke   +3 more
doaj   +1 more source

Therapeutic Applications of Programmable DNA Nanostructures

open access: yesMicromachines, 2022
Deoxyribonucleic acid (DNA) nanotechnology, a frontier in biomedical engineering, is an emerging field that has enabled the engineering of molecular-scale DNA materials with applications in biomedicine such as bioimaging, biodetection, and drug delivery ...
Seaim Lwin Aye, Yusuke Sato
doaj   +1 more source

Transmembrane capability of DNA origami sheet enhanced by 3D configurational changes

open access: yesiScience, 2023
Summary: DNA origami-engineered nanostructures are widely used in biomedical applications involving transmembrane delivery. Here, we propose a method to enhance the transmembrane capability of DNA origami sheets by changing their configuration from two ...
Fengyu Liu   +5 more
doaj   +1 more source

Rationally Designed DNA Nanostructures for Drug Delivery

open access: yesFrontiers in Chemistry, 2020
DNA is an excellent biological material that has received growing attention in the field of nanotechnology due to its unique capability for precisely engineering materials via sequence specific interactions.
Fan Xu, Qing Xia, Pengfei Wang
doaj   +1 more source

DNA Origami Nanomachines

open access: yesMolecules, 2018
DNA can assemble various molecules and nanomaterials in a programmed fashion and is a powerful tool in the nanotechnology and biology research fields.
Masayuki Endo, Hiroshi Sugiyama
doaj   +1 more source

Generating DNA Origami Nanostructures through Shape Annealing

open access: yesApplied Sciences, 2021
Structural DNA nanotechnology involves the design and self-assembly of DNA-based nanostructures. As a field, it has progressed at an exponential rate over recent years. The demand for unique DNA origami nanostructures has driven the development of design
Bolutito Babatunde   +3 more
doaj   +1 more source

Minimizing Cholesterol-Induced Aggregation of Membrane-Interacting DNA Origami Nanostructures

open access: yesMembranes, 2021
DNA nanotechnology provides methods for building custom membrane-interacting nanostructures with diverse functions, such as shaping membranes, tethering defined numbers of membrane proteins, and transmembrane nanopores.
Jasleen Kaur Daljit Singh   +5 more
doaj   +1 more source

DNA origami technology for biomedical applications: Challenges and opportunities

open access: yesMedComm – Biomaterials and Applications, 2023
DNA origami, a promising branch of structural DNA technology, refers to the technique of folding a single‐stranded DNA scaffold into well‐defined nanostructures.
Ling Li   +4 more
doaj   +1 more source

Enhanced structural stability of DNA origami nanostructures by graphene encapsulation

open access: yesNew Journal of Physics, 2016
We demonstrate that a single-layer graphene replicates the shape of DNA origami nanostructures very well. It can be employed as a protective layer for the enhancement of structural stability of DNA origami nanostructures. Using the AFM based manipulation,
Aleksandar Matković   +6 more
doaj   +1 more source

DNA-directed self-assembly of three-dimensional plasmonic nanostructures for detection by surface-enhanced Raman scattering (SERS)

open access: yesSensing and Bio-Sensing Research, 2014
Surface-enhanced Raman scattering (SERS) is a promising technology owing to its single-molecular sensitivity and molecular specificity. However, producing strong and stable SERS signal from plasmonic nanostructures remains a challenge. Herein, we present
Jung-Won Keum   +5 more
doaj   +1 more source

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