Results 11 to 20 of about 1,457,962 (138)

DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts. [PDF]

, 2002
Alkylating agents, such as methyl methanesulfonate (MMS), damage DNA and activate the DNA damage checkpoint. Although many of the checkpoint proteins that transduce damage signals have been identified and characterized, the mechanism that senses the ...
Lindsay, Howard D., Stokes, Matthew P., Van Hatten, Ruth, Howard D. Lindsay (4252681), Howard D. Lindsay, W. Matthew Michael, Ruth Van Hatten (16043837), W. Matthew Michael (3211092), Ruth Van Hatten, Matthew P. Stokes, Matthew P. Stokes (9707794), Michael, W. Matthew   +11 more
core   +5 more sources

A eubacterial origin for the human tRNA nucleotidyltransferase? [PDF]

, 2001
tRNA CCA-termini are generated and maintained by tRNA nucleotidyltransferases. Together with poly(A) polymerases and other enzymes they belong to the nucleotidyltransferase superfamily.
Mörl, M. ; https://orcid.org/, Mörl, Mario, Reichert, Andreas S., Thurlow, D., A.S. Reichert, M. Mörl, Reichert, A., Thurlow, D. L., Reichert, A. S., Mörl, M., D.L. Thurlow   +10 more
core   +1 more source

Analysis of Unusual Eukaryotic tRNA Nucleotidyltransferases and Establishment of a High-Throughput Sequencing Method for Mature tRNAs [PDF]

, 2020
Transfer RNA nucleotidyltransferases (CCA-adding enzymes) are important enzymes, which catalyze the attachment of a CCA triplet to the 3‘ end of tRNAs, an essential requirement for subsequent aminoacylation.
Erber, Lieselotte
core   +1 more source

Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III [PDF]

, 2006
SummaryBacterial replicative DNA polymerases such as Polymerase III (Pol III) share no sequence similarity with other polymerases. The crystal structure, determined at 2.3 Å resolution, of a large fragment of Pol III (residues 1–917), reveals a unique ...
Georgescu, Roxana E., Lamers, Meindert H., Lee, Sang-Gyu, Kuriyan, John, O'Donnell, Mike   +4 more
core   +1 more source

Genotoxikus hatásra bekövetkező funkcionális és strukturális DNS változások = Functional and structural changes in DNA upon genotoxic effects [PDF]

, 2008
Morfológiai és biokémiai vizsgálataink arra utalnak, hogy a a genotoxikus hatások kategorizálhatók az okozott kromatin változások alapján. A kemotoxikus változások potenciális diagnosztikus jelentősége miatt vizsgáltuk a nehézfémek (elsősosrban kadmium) (
Szepessy, Edit, Rőszer, Tamás, Bánfalvi, Gáspár, Jenei, Zsolt, Serfőző, Zoltán, Nagy, Gábor György, B. Kiss, Zsigmond   +6 more
core   +1 more source

Electronic transport in DNA [PDF]

, 2005
We study the electronic properties of DNA by way of a tight-binding model applied to four particular DNA sequences. The charge transfer properties are presented in terms of localization lengths (crudely speaking, the length over which electrons travel).
Klotsa, Daphne, Turner, Matthew S., Römer, Rudolf A., Roemer, Rudolf A.   +3 more
core   +1 more source

Cellular Processing Pathways Contribute to the Activation of Etoposide- Induced DNA Damage Responses

, 2009
Cytotoxic action (tumor cell killing) and carcinogenic side effect ( therapy-related secondary leukemia) of etoposide are closely related to its ability in stabilizing topoisomerase II cleavable complex (TOP2cc), a unique form of protein- linked DNA ...
FAN, JIA-RONG;PENG, AN-LIN;LO, SHU-CHI;HUANG, TING-HSIANG;LI, TSAI-KUN, 范嘉榕;彭安林;羅淑祺;黃鼎翔;李財坤   +1 more
core   +1 more source

Molecular mechanisms and kinetics between DNA and DNA binding ligands [PDF]

, 2005
Sischka A, Tönsing K, Eckel R, et al. Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophysical Journal. 2005;88(1):404-411.Mechanical properties of single double-stranded DNA (dsDNA) in the presence of different binding ligands ...
Anselmetti, Dario, Wilking, Sven David, Ros, Robert, Toensing, Katja, Sischka, Andy, Eckel, Rainer, Sewald, Norbert, Tönsing, Katja, Sewald, Norbert ; https://orcid.org/, Anselmetti, Dario ; https://orcid.org/   +9 more
core   +1 more source

Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases [PDF]

, 2004
ATP(CTP):tRNA nucleotidyl transferases, tRNA maturing enzymes found in all organisms, and eubacterial poly(A) polymerases, enzymes involved in mRNA degradation, are so similar that until now their biochemical functions could not be distinguished by their
Keller, W., Martin, G.
core  

Nutrient disturbance in a shallow aquaculture pond impacts Microcystis gene expression but does not impact bacterial community function during bloom conditions

Journal of Phycology, Volume 62, Issue 4, Page 1297-1310, August 2026.
Abstract Cyanobacterial harmful algal blooms (cHABs) are worldwide issues. Reduced nitrogen forms (ammonium and urea) have recently been measured in freshwater systems at concentrations not previously recorded. These reduced nitrogen forms have been shown to favor the proliferation of harmful cyanobacteria.
Matthew F. Gladfelter, Hunter R. Baylous, Alan E. Wilson, Morgan M. Steffen   +3 more
wiley   +1 more source