Results 51 to 60 of about 6,590 (201)

Synthesis of DNA Origami Scaffolds: Current and Emerging Strategies

Molecules, 2020
DNA origami nanocarriers have emerged as a promising tool for many biomedical applications, such as biosensing, targeted drug delivery, and cancer immunotherapy.
Joshua Bush, Shrishti Singh, Merlyn Vargas, Esra Oktay, Chih-Hsiang Hu, Remi Veneziano   +5 more
doaj   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Pathway Complexity Defines the Shape of Nucleic Acid‐Loaded Polyion Complex Micelles: Spheroids vs. Hexagonal Disks

Angewandte Chemie, EarlyView.
Same building blocks, different destinies. Pathway complexity directs nucleic acid–loaded polyion complex micelles along distinct assembly trajectories, resulting in either hexagonally shaped or spheroidal nanoparticles with distinct internal structuring.
Lennart van den Hoven, Neshat Moslehi, Eline F. Brink, Austin Hubley, Ilja K. Voets, Tina Vermonden, Elham Mirzahossein, Bas G. P. van Ravensteijn   +7 more
wiley   +2 more sources

High-speed 3D DNA PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography

Nature Communications
DNA origami information storage is a promising alternative to silicon-based data storage, offering a molecular cryptography technique concealing information within DNA origami.
Gde Bimananda Mahardika Wisna, Daria Sukhareva, Jonathan Zhao, Prathamesh Chopade, Deeksha Satyabola, Michael Matthies, Subhajit Roy, Chao Wang, Petr Šulc, Hao Yan, Rizal F. Hariadi   +10 more
doaj   +1 more source

A Methodology for Validation of DNA Origami–Quantum Dot Hybridization

Applied Nano
Since the introduction of the DNA origami technology by Seeman and Rothemund, the integration of functional entities (nanoparticles, quantum dots, antibodies, etc.) has been of huge interest to broaden the area of applications for this technology.
Mathis Janßen, Anastasiia D. Murkina, Julia Hann, Gunnar Klös, Martin Moebius, Christoph R. Meinecke, Andreas Morschhauser, Aitziber L. Cortajarena, Danny Reuter   +8 more
doaj   +1 more source

Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping

Advanced Science, EarlyView.
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron, Bokun Zheng, Ziyang Zhou, Noel Naughton, Suyi Li   +4 more
wiley   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

DNA Origami Route for Nanophotonics [PDF]

ACS Photonics, 2018
The specificity and simplicity of the Watson-Crick base pair interactions make DNA one of the most versatile construction materials for creating nanoscale structures and devices. Among several DNA-based approaches, the DNA origami technique excels in programmable self-assembly of complex, arbitrary shaped structures with dimensions of hundreds of ...
Anton Kuzyk, Ralf Jungmann, Guillermo P. Acuna, Na Liu   +3 more
openaire   +6 more sources

Structural stability of DNA origami nanostructures under application-specific conditions

Computational and Structural Biotechnology Journal, 2018
With the introduction of the DNA origami technique, it became possible to rapidly synthesize almost arbitrarily shaped molecular nanostructures at nearly stoichiometric yields.
Saminathan Ramakrishnan, Heini Ijäs, Veikko Linko, Adrian Keller   +3 more
doaj   +1 more source

Self-assembled endogenous DNA nanoparticles for auto-release and expression of the eGFP gene in Bacillus subtilis

Communications Biology, 2022
The DNA origami design algorithm DAEDALUS is modified to design a nanoscale cube with a two-step assembly protocol, assembling 9 modules from three DNA scaffolds and the complementary staples, combined to form the DNA origami cube.
Linfeng Cao, Ziwen Meng, Junjie Tan, Ming Ying, Meiying Bi, Yanjun Liu, Xinrui Tong, Jiaxun Wei, Lei Huang   +8 more
doaj   +1 more source