Results 61 to 70 of about 6,590 (201)
DNA Switching Circuits Based on Binary Tree
IEEE Access, 2021 Switching circuits provide an interesting strategy for modularization construction of digital computing. Multi-step reactions on DNA origami template are essentially the same as switching circuits.
Zhao Chen +4 more
doaj +1 more source
Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma
Advanced Science, EarlyView.Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul +4 more
wiley +1 more source
DNA origami directed fabrication of shape-controllable nanomaterials
APL Materials, 2020 Precise control over the morphologies of nanomaterials is of great importance in nanoscience, as the properties of nanomaterials are strongly dependent on their size, shape, and composition.
Fengsong Liu +5 more
doaj +1 more source
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
Advanced Science, EarlyView.CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source
Small StructuresDNA origami nanostructures are promising carries for drug delivery applications. However, their limited stability under relevant conditions often presents a challenge.
Lukas Rabbe +3 more
doaj +1 more source
Molecular mechanics of DNA bricks: in situ structure, mechanical properties and ionic conductivity
New Journal of Physics, 2016 The DNA bricks method exploits self-assembly of short DNA fragments to produce custom three-dimensional objects with subnanometer precision. In contrast to DNA origami, the DNA brick method permits a variety of different structures to be realized using ...
Scott Michael Slone +3 more
doaj +1 more source
Quantifying Structure‐Dependent Rigidity of 3D DNA Origami Boxes
Advanced Intelligent Systems, EarlyView.We investigate the mechanical stability of a hollow 3D DNA origami box during assembly using liquid AFM imaging and finite element simulations. As structural completeness increases from flat sheets through intermediate assemblies to a closed box, rigidity improves.
Judith Zubia‐Aranburu +5 more
wiley +1 more source
Ion beam processing of DNA origami nanostructures
Beilstein Journal of NanotechnologyDNA origami nanostructures are emerging as a bottom-up nanopatterning approach. Direct combination of this approach with top-down nanotechnology, such as ion beams, has not been considered because of the soft nature of the DNA material.
Leo Sala +8 more
doaj +1 more source
DNA Aptamers for the Functionalisation of DNA Origami Nanostructures [PDF]
Genes, 2018 DNA origami has emerged in recent years as a powerful technique for designing and building 2D and 3D nanostructures. While the breadth of structures that have been produced is impressive, one of the remaining challenges, especially for DNA origami structures that are intended to carry out useful biomedical tasks in vivo, is to endow them with the ...
Yusuke Sakai +5 more
openaire +2 more sources
Molecular Origami: Designing Functional Molecules of the Future
MoleculesIn the field of chemical biology, DNA origami has been actively researched. This technique, which involves folding DNA strands like origami to assemble them into desired shapes, has made it possible to create complex nanometer-sized structures, marking a
Hitoshi Ishida +2 more
doaj +1 more source