Results 161 to 170 of about 898,091 (296)

Small molecules restore mutant mitochondrial DNA polymerase activity. [PDF]

Nature
Valenzuela S, Zhu X, Macao B, Stamgren M, Geukens C, Charifson PS, Kern G, Hoberg E, Jenninger L, Gruszczyk AV, Lee S, Johansson KAS, Miralles Fusté J, Shi Y, Kerns SJ, Arabanian L, Martinez Botella G, Ekström S, Green J, Griffin AM, Pardo-Hernández C, Keating TA, Küppers-Munther B, Larsson NG, Phan C, Posse V, Jones JE, Xie X, Giroux S, Gustafsson CM, Falkenberg M.   +30 more
europepmc   +1 more source

On the processive mechanism of Escherichia coli DNA polymerase I. Quantitative assessment of processivity.

, 1978
Robert A. Bambara, Dennis G. Uyemura, Tae‐Jin Choi   +2 more
openalex   +1 more source

Reconstitution of bacterial DNA‐dependent RNA‐polymerase from isolated subunits as a tool for the elucidation of the role of the subunits in transcription [PDF]

, 1970
Alfred Heil, Wolfram Zillig
openalex   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair. [PDF]

Nucleic Acids Res
Inanc B, Fang Q, Roos WP, Andrews JF, Zeng X, Clark J, Li J, Dey NB, Ibrahim M, Sykora P, Yu Z, Pearson CR, Braganza A, Verheij M, Jonkers J, Yates NA, Vens C, Sobol RW.   +17 more
europepmc   +1 more source

Phosphorylation of yeast DNA-dependent RNA polymerases in vivo and in vitro. Isolation of enzymes and identification of phosphorylated subunits.

, 1977
Graeme I. Bell, Pablo Valenzuela, William J. Rutter   +2 more
openalex   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Processiveness of DNA polymerases. A comparative study using a simple procedure.

, 1979
Somdipto Das, Robert K. Fujimura
openalex   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes. [PDF]

J Vis Exp
Kusi-Appauh N, Mueller SH, Ralph SF, Yurieva O, O'Donnell ME, Lewis JS, Spenkelink LM.   +6 more
europepmc   +1 more source