Results 171 to 180 of about 954,914 (266)

CRISPR-DNA Polymerase Assisted Targeted Mutagenesis for Regulable Laboratory Evolution. [PDF]

Adv Sci (Weinh)
Chen S, Chen X, Peng Y, Li Q, Zhou J, Li J, Du G, Chen J, Zhang G.   +8 more
europepmc   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

Post-PCR Labeling Using Taq DNA Polymerase

BioTechniques, 1997
Zhidong Chen, Duane E. Ruffner
doaj   +1 more source

Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation. [PDF]

Nucleic Acids Res
Moreno NC, Korchak EJ, Latancia MT, D'Orlando DA, Adegbenro T, Barnes RP, Bezsonova I, Woodgate R, Ashton NW.   +8 more
europepmc   +1 more source

Yeast mitochondrial DNA polymerase is related to the family A DNA polymerases

Nucleic Acids Research, 1990
J, Ito, D K, Braithwaite
openaire   +3 more sources

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source

The non-catalytic DNA polymerase ε subunit is an NPF motif recognition protein. [PDF]

Nat Commun
Keskitalo S, Zambo B, Malaymar Pinar D, Tuhkala A, Salokas K, Turunen T, Deutsch N, Davey N, Dosztányi Z, Varjosalo M, Gogl G.   +10 more
europepmc   +1 more source

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

Advanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai, Zhiying Yang, Zongguang Liu, Wanjia Hu, Lixiao Ma, Enze Kang, Wanqing Luo, Yunpeng Zhao, Chengzhu Liu, Juan Jia, Ting Liu, Chen He, Quan Shi, Jianliang Liu, Yongheng Gao, Huai Chen, Hailong Zhang, Meixun Zhao, Xiaojuan Feng   +18 more
wiley   +1 more source

Cryo-EM maps of human DNA polymerase ε should be reevaluated in light of its unexpected behavior in vitro. [PDF]

Proc Natl Acad Sci U S A
Roske JJ, Yeeles JTP.
europepmc   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source