Results 201 to 210 of about 812,933 (320)

Strand-selective repair of DNA damage in the yeast GAL7 gene requires RNA polymerase II

, 1992
Steven A. Leadon, David A. Lawrence
openalex   +1 more source

Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro [PDF]

, 2002
Keng‐Boon Lee, Dong Wang, Stephen J. Lippard, Phillip A. Sharp   +3 more
openalex   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein-bound nick in the DNA template. [PDF]

FEBS Lett
Herring P, Roedgaard M, Holst CM, Christensen H, Knudsen BR, Bjergbaek L, Andersen AH.   +6 more
europepmc   +1 more source

Introduction of specific point mutations into RNA polymerase II by gene targeting in mouse embryonic stem cells: evidence for a DNA mismatch repair mechanism.

, 1990
C M Steeg, James Ellis, A Bernstein
openalex   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

The plusses and minuses of DNA torsion. [PDF]

Elife
Henikoff S, Levens DL.
europepmc   +1 more source

Two Subunits of Wheat Germ, Calf Thymus and Human Placenta DNA-dependent RNA Polymerases II Bind to DNA

, 1990
Young Ik Lee, Stefan S. Surzycki
openalex   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Ancient Host-Virus Gene Transfer Hints at a Diverse Pre-LECA Virosphere. [PDF]

J Mol Evol
Karki S, Barth ZK, Aylward FO.
europepmc   +1 more source