Use of Site-Specific Protein-DNA Photocrosslinking to Analyze the Molecular Organization of the RNA Polymerase II Initiation Complex [PDF]
François Robert, Benoit Coulombe
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Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang+11 more
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Dual synthesis pathways of scaRNA28 via intronic processing of transformation/transcription domain-associated protein transcripts and a novel independent transcription unit. [PDF]
Izumikawa K+8 more
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Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA [PDF]
Taurai Tasara
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Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
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Guanine quadruplexes mediate mitochondrial RNA polymerase pausing. [PDF]
Snyder RJ+6 more
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Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao+7 more
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An ultrasensitive and specific CRISPR-Cas13a-mediated point-of-care assay for monkeypox detection and PCR-based clade detection. [PDF]
Zhang Q+8 more
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Cyclin D1 activation in B-cell malignancy: association with changes in histone acetylation, DNA methylation, and RNA polymerase II binding to both promoter and distal sequences [PDF]
Hui Liu, Jin Wang, Elliot Epner
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This study developed a nitrogen‐strengthened copper‐iron‐zinc (N‐CuFeZn) alloy bioactive dressing integrated with electromagnetic stimulation. The coaxial dressing, made from 0.04 mm filaments with 1120 MPa tensile strength, showed that electromagnetic activation enhanced therapeutic outcomes by increasing VEGF expression, promoting angiogenesis (2.1 ...
Xiaohui Qiu+9 more
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