Results 291 to 300 of about 1,237,824 (318)
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Nature, 1970
A membrane associated DNA polymerizing enzyme has been solubilized, partially isolated and characterized.
R. Knippers
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A membrane associated DNA polymerizing enzyme has been solubilized, partially isolated and characterized.
R. Knippers
semanticscholar +4 more sources
Crystallization of DNA polymerase II from Escherichia coli.
Journal of Molecular Biology, 1994DNA polymerase II of Escherichia coli, an alpha-like or group B polymerase, has been crystallized. The crystals are orthorhombic, space group P2(1)2(1)2, with cell dimensions a = 94.4 A, b = 118.2 A, c = 84.2 A and diffract to at least 3.0 A resolution. This is the first example of a group B polymerase to be crystallized.
W. Anderson +4 more
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Molecular modeling of RNA polymerase II mutations onto DNA polymerase I.
Journal of Molecular Biology, 1994Genetic and molecular analysis in Drosophila melanogaster identifies eight suppressor mutations in the second largest subunit of RNA polymerase II. The suppressor mutations fall into two classes: five are strong, result from the same serine to cysteine amino acid residue substitution and rescue one conditional lethal allele in the largest subunit of ...
W. Kim, L. P. Burke, M. Mortin
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Inhibition of E. coli DNA polymerase II by ara-CTP.
Nature New Biology, 1971THE potent antileukaemic agent, 1-β-D-arabinofuranosylcytosine (ara-C), specifically inhibits DNA synthesis in bacterial and animal cells1,2. Although the exact mechanism of inhibition has been in doubt, it seems likely that it occurs at the DNA polymerization reaction itself2–5. We describe here the effects of ara-CTP, which is the most prominent form
G. V. Rama Reddy, M. Goulian, S. Hendler
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DNA Polymerase II, the Epsilon Polymerase of Saccharomyces cerevisiae
1993Publisher Summary This chapter discusses the data on DNA polymerase II in the context of current knowledge of eukaryotic DNA polymerases, DNA replication and its fidelity, and DNA repair. DNA polymerase II has been proffered as the “repair polymerase.” Contrary to the implicit assumption, DNA repair is not a single process but an array of different ...
A, Morrison, A, Sugino
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DNA Melting on Yeast RNA Polymerase II Promoters
Science, 1993Transcription-dependent DNA melting on the yeast GAL1 and GAL10 promoters was found to be more closely correlated with the TATA box than the transcription start site. On both these genes, melting begins about 20 base pairs downstream of the TATA box. Physical and genetic analyses suggest that
C, Giardina, J T, Lis
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RNA polymerase II associates with active genes during DNA replication
Nature, 2023The transcriptional machinery is thought to dissociate from DNA during replication. Certain proteins, termed epigenetic marks, must be transferred from parent to daughter DNA strands in order to maintain the memory of transcriptional states1,2. These proteins are believed to re-initiate rebuilding of chromatin structure, which ultimately recruits RNA ...
Tyler K. Fenstermaker +4 more
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