Modular fluorescent nanoparticle DNA probes for detection of peptides and proteins. [PDF]
Stawicki CM +8 more
europepmc +1 more source
Feasibility of in situ hybridisation with chromosome specific DNA probes on paraffin wax embedded tissue. [PDF]
E.P.J. Arnoldus +8 more
openalex +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
We report an approach for in situ detection of genomic DNA sequences, where transiently opening DNA duplexes are captured by circularizing DNA strands - padlock probes - that lock in place in a sequence-specific manner through the action of a DNA ligase.
Ryoyo Ikebuchi +8 more
doaj +1 more source
Programming Fluorogenic DNA Probes for Rapid Detection of Steroids. [PDF]
Ebrahimi SB +8 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Fluorescent aptasensor for detection of live foodborne pathogens based on multicolor perovskite-quantum-dot-encoded DNA probes and dual-stirring-bar-assisted signal amplification. [PDF]
Liu L +6 more
europepmc +1 more source
Faculty Opinions recommendation of High-density microarray of small-subunit ribosomal DNA probes.
David A. Relman
openalex +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Probing the mutation independent interaction of DNA probes with SARS-CoV-2 variants through a combination of surface-enhanced Raman scattering and machine learning. [PDF]
Moitra P +7 more
europepmc +1 more source

