Results 241 to 250 of about 792,120 (349)

Effect of co-axially hybridized gene targets on hybridization efficiency of microarrayed DNA probes

, 2010
Kai Jiang, Jie-Len Huang, Chia‐Chun Chen, Hung-Ju Su, Jui‐Chuang Wu   +4 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Development of DNA Probes for the Detection and Identification of Babesia ovata

, 1993
Shin‐ichiro Kawazu, Chandrawathani Panchadcharam, Takeshi Kawazu, Tsutomu Sekizaki, Kozo Fujisaki   +4 more
openalex   +1 more source

Probing a Major DNA Weakness: Resolving the Groove and Sequence Selectivity of the Diimine Complex Λ‐[Ru(phen)₂phi]²⁺ [PDF]

Tayler D. Prieto Otoya, Kane T. McQuaid, Joseph Hennessy, Georgia Menounou, Alex Gibney, Neil G. Paterson, David J. Cardin, Andrew Kellett, Christine J. Cardin   +8 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

One probe fits all: a highly customizable modular RNA in situ hybridization platform expanding the application of SABER DNA probes.

Development
Ustyantsev K, Stranges M, Volpe FG, de Boer JF, Kuipers F, Mouton S, Berezikov E.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Cloned single copy DNA sequences of Mycobacterium tuberculosis as DNA probes.

, 1991
Prabhakara P. Reddi, Talwar Gp, Khandekar Ps   +2 more
openalex   +1 more source

Detection of the Philippine Isolate of Rice Yellow Dwarf (RYD) Agent Using DNA Probes

, 1992
K. Nakashima, H. Koganezawa, P. Q. Cabauatan   +2 more
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source