Results 31 to 40 of about 3,796,516 (329)
Development and application of DNA molecular probes
AIMS Bioengineering, 2017 The development of DNA probes started from 1950's for diagnostic purposes and it is still growing. DNA probes are applied in several fields such as food, medical, veterinary, environment and security, with the aim of prevention, diagnosis and treatment ...
Priya Vizzini +3 more
doaj +1 more source
Furan-PNA : a mildly inducible irreversible interstrand crosslinking system targeting single and double stranded DNA [PDF]
, 2016 We here report on the design and synthesis of tailor-made furan-modified peptide nucleic acid (PNA) probes for covalent targeting of single stranded DNA through a crosslinking strategy.
Corradini, Roberto +3 more
core +2 more sources
Fluorescent DNA hybridization probe preparation using amine modification and reactive dye coupling
BioTechniques, 2004 Fluorescent nucleic acid hybridization probes traditionally have been generated by enzymatic incorporation of dye-labeled nucleotides, even though incorporation efficiency is low and variable from dye to dye.
W. Gregory Cox, Victoria L. Singer
doaj +1 more source
Influence of the environment and probes on rapid DNA sequencing via transverse electronic transport [PDF]
, 2007 We study theoretically the feasibility of using transverse electronic transport within a nanopore for rapid DNA sequencing. Specifically, we examine the effects of the environment and detection probes on the distinguishability of the DNA bases.
Akeson +44 more
core +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 1977 We describe a technique for transferring electrophoretically separated bands of RNA from an agarose gel to paper strips. The RNA is coupled covalently to diazobenzyloxymethyl groups on the paper.
J. Alwine, D. Kemp, G. Stark
semanticscholar +1 more source
DNA tetrahedron for fluorescence anisotropy of intercalators
He jishu, 2021 BackgroundThe fluorescence anisotropy of intercalative dye plays important roles in nucleic acid analysis, the construction of fluorescent probes, and biosensing.
HUANG Qiuling +4 more
doaj +1 more source
A Technical Note on Quantum Dots for Multi-Color Fluorescence in situ Hybridization [PDF]
, 2009 Quantum dots (Qdots) are semiconductor nanocrystals, which are photo-stable, show bright fluorescence with narrow, symmetric emission spectra and are available in multiple resolvable colors.
Cremer, M. +4 more
core +1 more source
DNA probe for Aeromonas salmonicida [PDF]
Applied and Environmental Microbiology, 1992 A DNA fragment that is specific to Aeromonas salmonicida has been isolated from a genomic DNA library by differential hybridization. The specificity of this fragment as a DNA probe for A. salmonicida was shown by hybridization against reference strains and clinical isolates of A. salmonicida, related aeromonads, and species from several other bacterial
Frank Gannon +5 more
openaire +3 more sources
Molecules, 2018 Sequence-specific detection of nucleic acids has been intensively studied in the field of molecular diagnostics. In particular, the detection and analysis of single-nucleotide polymorphisms (SNPs) is crucial for the identification of disease-causing ...
Gil Tae Hwang
doaj +1 more source
DNA Stable-Isotope Probing (DNA-SIP) [PDF]
Journal of Visualized Experiments, 2010 DNA stable-isotope probing (DNA-SIP) is a powerful technique for identifying active microorganisms that assimilate particular carbon substrates and nutrients into cellular biomass. As such, this cultivation-independent technique has been an important methodology for assigning metabolic function to the diverse communities inhabiting a wide range of ...
Eric A. Dunford, Josh D. Neufeld
openaire +3 more sources