Results 11 to 20 of about 473,267 (264)

A novel cassette method for probe evaluation in the designed biochips. [PDF]

open access: yesPLoS ONE, 2014
A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Vitaly Zinkevich   +7 more
doaj   +1 more source

Use of the Illumina EPIC methylation array for epigenomic research in the crab‐eating macaque (Macaca fascicularis)

open access: yesNeuropsychopharmacology Reports, 2020
Background Commercially available Illumina DNA methylation arrays (HumanMethylation 27K, HumanMethylation450, and MethylationEPIC BeadChip) can be used for comprehensive DNA methylation analyses of not only the human genome but also other mammalian ...
Yutaka Nakachi   +4 more
doaj   +1 more source

Electrochemical DNA Probes

open access: yesAnalytical Letters, 1996
A report on the status of the electrochemical DNA probes for the detection of a DNA sequence for environmental and clinical studies is presented. The literature on the electrochemistry of DNA in the last ten years is reviewed. Results obtained in this laboratory using an electroactive hybridization indicator for constructing an electrochemical DNA ...
S. Palanti   +2 more
openaire   +2 more sources

DNA probe for Aeromonas salmonicida [PDF]

open access: yesApplied and Environmental Microbiology, 1992
A DNA fragment that is specific to Aeromonas salmonicida has been isolated from a genomic DNA library by differential hybridization. The specificity of this fragment as a DNA probe for A. salmonicida was shown by hybridization against reference strains and clinical isolates of A. salmonicida, related aeromonads, and species from several other bacterial
M, Hiney   +5 more
openaire   +2 more sources

The application of species specific DNA-targeted probes and fluorescently tagged lectin to differentiate several species of Pseudo-nitzschia (Bacillophyceae) in Chinhae Bay, Korea

open access: yesScientia Marina, 2001
We applied molecular methods using a DNA probe and fluorescently tagged lectins to discriminate toxic Pseudo-nitzschia multiseries from the Chinhae Bay for a Korean harmfulalgae monitoring program. From the binding activity of lectins, P. multistriata, P.
Eun Seob Cho   +3 more
doaj   +1 more source

Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes

open access: yesMolecules, 2015
Development of probes that allow for sequence-unrestricted recognition of double-stranded DNA (dsDNA) continues to attract much attention due to the prospect for molecular tools that enable detection, regulation, and manipulation of genes.
Brooke A. Anderson   +2 more
doaj   +1 more source

Quantitative Analysis of Nucleic Acid Hybridization on Magnetic Particles and Quantum Dot-Based Probes

open access: yesSensors, 2009
In the present study we describe sandwich design hybridization probes consisting of magnetic particles (MP) and quantum dots (QD) with target DNA, and their application in the detection of avian influenza virus (H5N1) sequences. Hybridization of 25-, 40-,
Alexey Dan Chin Yu   +4 more
doaj   +1 more source

Fluorescent DNA hybridization probe preparation using amine modification and reactive dye coupling

open access: yesBioTechniques, 2004
Fluorescent nucleic acid hybridization probes traditionally have been generated by enzymatic incorporation of dye-labeled nucleotides, even though incorporation efficiency is low and variable from dye to dye.
W. Gregory Cox, Victoria L. Singer
doaj   +1 more source

Fluorescent Probes of DNA Repair [PDF]

open access: yesACS Chemical Biology, 2017
DNA repair is now understood to play a key role in a variety of disease states, most notably cancer. Tools for studying DNA have typically relied on traditional biochemical methods which are often laborious and indirect. Efforts to study the biology and therapeutic relevance of DNA repair pathways can be limited by such methods.
David L. Wilson, Eric T. Kool
openaire   +2 more sources

DNA tetrahedron for fluorescence anisotropy of intercalators

open access: yesHe jishu, 2021
BackgroundThe fluorescence anisotropy of intercalative dye plays important roles in nucleic acid analysis, the construction of fluorescent probes, and biosensing.
HUANG Qiuling   +4 more
doaj   +1 more source

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