Results 51 to 60 of about 3,796,516 (329)

Probing helical transitions in a DNA duplex [PDF]

open access: yesPhysical Chemistry Chemical Physics, 2017
Conformational switch from B-DNA to Z-DNA, an energy landscape perspective.
Wales, DJ, Chakraborty, Debayan
openaire   +3 more sources

Long Oligonucleotide Arrays on Nylon for Large-Scale Gene Expression Analysis

open access: yesBioTechniques, 2002
To date, most studies of multigenic expression patterns by long DNA array have used DNA fragments as probes. These probes are usually obtained as PCR products, and this represents a time-consuming and error-prone approach, requiring strict quality ...
M. El Atifi   +5 more
doaj   +1 more source

DNA multi-bit non-volatile memory and bit-shifting operations using addressable electrode arrays and electric field-induced hybridization. [PDF]

open access: yes, 2018
DNA has been employed to either store digital information or to perform parallel molecular computing. Relatively unexplored is the ability to combine DNA-based memory and logical operations in a single platform.
Heller, Michael J   +3 more
core   +3 more sources

Direct probing: covalent attachment of probe DNA to double-stranded target DNA [PDF]

open access: yesNucleic Acids Research, 1998
We report a novel procedure, which can be applied to probing of specific DNA, for covalently attaching probe DNA to complementary sequences in double-stranded target DNA. Employing hairpin-like oligonucleotide probes in combination with successive use of recA protein and DNA ligase, probes can be attached directly to target DNA molecules without ...
Michio Oishi, Jun Fujiwara
openaire   +3 more sources

Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. [PDF]

open access: yes, 2019
Migration through 3D constrictions can cause nuclear rupture and mislocalization of nuclear proteins, but damage to DNA remains uncertain, as does any effect on cell cycle.
Bannister   +77 more
core   +1 more source

DNA-based digital tension probes reveal integrin forces during early cell adhesion

open access: yesNature Communications, 2014
Mechanical stimuli profoundly alter cell fate, yet the mechanisms underlying mechanotransduction remain obscure because of a lack of methods for molecular force imaging.
Yun Zhang   +3 more
semanticscholar   +1 more source

Detailed kinship estimation for detecting bias among breeding families in a reintroduced population of the endangered bagrid catfish Tachysurus ichikawai

open access: yesPopulation Ecology, EarlyView.
In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno   +5 more
wiley   +1 more source

An inexpensive and simple method for thermally stable immobilization of DNA on an unmodified glass surface: UV linking of poly(T)10-poly(C)10–tagged DNA probes

open access: yesBioTechniques, 2008
Microarrays printed on glass slides are often constructed by covalently linking modified oligonucleotide probes to a derivatized surface at considerable expense.
Haukur Gudnason   +3 more
doaj   +1 more source

Optimal SNP filtering strategies for pedigree reconstruction: A case study with wild red‐spotted masu salmon population

open access: yesPopulation Ecology, EarlyView.
In this article, we tested optimal SNP filtering strategies for accurate parentage assignment and pedigree reconstruction for a wild population of red‐spotted masu salmon, Oncorhynchus masou ishikawae. We found that mid‐point filtering in terms of call rate and minor allele frequency performs well for pedigree reconstruction.
Shohei Noda   +6 more
wiley   +1 more source

Superior structure stability and selectivity of hairpin nucleic acid probes with an l-DNA stem [PDF]

open access: yes, 2007
Hairpin nucleic acid probes have been highly useful in many areas, especially for intracellular and in vitro nucleic acid detection. The success of these probes can be attributed to the ease with which their conformational change upon target binding can ...
Kim, Youngmi   +2 more
core   +3 more sources

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