Results 51 to 60 of about 789,440 (249)

A Technical Note on Quantum Dots for Multi-Color Fluorescence in situ Hybridization [PDF]

open access: yes, 2009
Quantum dots (Qdots) are semiconductor nanocrystals, which are photo-stable, show bright fluorescence with narrow, symmetric emission spectra and are available in multiple resolvable colors.
Cremer, M.   +4 more
core   +1 more source

Thermodynamics and kinetics guided probe design for uniformly sensitive and specific DNA hybridization without optimization

open access: yesNature Communications, 2019
Optimisation of nucleic acid probes and blocker strands can be laborious. Here the authors construct a theoretical model of competitive DNA hybridisation to design DNA probes for optimisation-free mutation detection.
Xin Chen   +10 more
doaj   +1 more source

Chemically programmable bacterial probes for the recognition of cell surface proteins

open access: yesMaterials Today Bio, 2023
Common methods to label cell surface proteins (CSPs) involve the use of fluorescently modified antibodies (Abs) or small-molecule-based ligands. However, optimizing the labeling efficiency of such systems, for example, by modifying them with additional ...
Pragati K. Prasad   +7 more
doaj   +1 more source

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

open access: yes, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W.   +3 more
core   +1 more source

Chromosome-specific DNA Repeat Probes [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 2006
In research as well as in clinical applications, fluorescence in situ hybridization (FISH) has gained increasing popularity as a highly sensitive technique to study cytogenetic changes. Today, hundreds of commercially available DNA probes serve the basic needs of the biomedical research community. Widespread applications, however, are often limited by
Baumgartner, Adolf   +2 more
openaire   +4 more sources

Orchestrated transcription of biological processes in the marine picoeukaryote Ostreococcus exposed to light/dark cycles [PDF]

open access: yes, 2010
Background: Picoeukaryotes represent an important, yet poorly characterized component of marine phytoplankton. The recent genome availability for two species of Ostreococcus and Micromonas has led to the emergence of picophytoplankton comparative ...
Bouget, François-Yves   +7 more
core   +7 more sources

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

open access: yesClinical Epigenetics, 2019
Background Alzheimer’s disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer’s disease have been unable to distinguish between DNA methylation and ...
Adam R. Smith   +11 more
doaj   +1 more source

CIN2+ detection of the HPV DNA Array genotyping assay in comparison with the Cobas 4800 HPV test and cytology [PDF]

open access: yes, 2019
BACKGROUND: HPV DNA Array is an E1-targeting PCR genotyping test, with capability of distinguishing 18 high-risk (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82) and 11 low-risk HPV types (6, 11, 40, 42, 44, 54, 67, 69, 70, 85 ...
Agorastos, Theodoros   +6 more
core   +1 more source

Changes in the subgingival biofilm composition after coronally positioned flap

open access: yesJournal of Applied Oral Science, 2011
OBJECTIVES: This study evaluated the effects of coronally positioned flap (CPF) on the subgingival biofilm composition. MATERIAL AND METHODS: Twenty-two subjects with gingival recessions were treated with CPF. Clinical parameters were assessed before and
Jadson Almeida Lima   +4 more
doaj   +1 more source

Probing Rad51-DNA interactions by changing DNA twist [PDF]

open access: yesNucleic Acids Research, 2012
In eukaryotes, Rad51 protein is responsible for the recombinational repair of double-strand DNA breaks. Rad51 monomers cooperatively assemble on exonuclease-processed broken ends forming helical nucleo-protein filaments that can pair with homologous regions of sister chromatids.
Atwell, Scott   +7 more
openaire   +7 more sources

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