Results 181 to 190 of about 3,766,607 (390)

Interaction between two error-prone DNA repair systems inEscherichia coli [PDF]

, 1977
C. Monti‐Bragadin, S. Venturini, Peter A. Todd   +2 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Molecular profiling of biliary tract cancers reveals distinct genomic landscapes between circulating and tissue tumor DNA

Experimental Hematology & Oncology
Biliary tract cancers (BTCs) are heterogeneous malignancies with dismal prognosis due to tumor aggressiveness and poor response to limited current therapeutic options.
Clémence Astier, Carine Ngo, Léo Colmet-Daage, Virginie Marty, Olivia Bawa, Claudio Nicotra, Maud Ngo-Camus, Antoine Italiano, Christophe Massard, Jean-Yves Scoazec, Cristina Smolenschi, Michel Ducreux, Antoine Hollebecque, Sophie Postel-Vinay   +13 more
doaj   +1 more source

Human uracil DNA N-glycosidase: studies in normal and repair defective cultured fibroblasts [PDF]

, 1978
U. Kühnlein, Betty Lee, Stuart Linn
openalex   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Binding of a Nitroxyl to Radiation-induced DNA Transients in Repair and Repair Deficient of E. coli K-12. [PDF]

, 1975
Einar Wold, Tor Brustad, E. Kulonen, Juhani Jänne, Synnøve Liaaen‐Jensen   +4 more
openalex   +1 more source

The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

Nature reviews. Molecular cell biology, 2020
M. Tarsounas, P. Sung
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Developmental decline in DNA repair in neural retina cells of chick embryos: persistent deficiency of repair competence in a cell line derived from late [PDF]

, 1977
Peter Karran, A.A. Moscona, Bernard S. Strauss   +2 more
openalex   +1 more source

DNA Repair in Cancer [PDF]

Journal of Oncology, 2019
Yintao Li, Qingyuan Yang, Zhihua Kang, Zhihua Kang   +3 more
openaire   +3 more sources