Results 211 to 220 of about 981,272 (286)

DNA repair pathway-related proteins are involved in the circularization step of microDNA eccDNA^fib-L. [PDF]

Commun Biol
Tong X, Qiu Q, Hu X, Liu Z, Yin M, Li L, Lei C, Feng Y, Zhu M, Gong C.   +9 more
europepmc   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Dysregulated mitochondrial homeostasis and DNA repair in the progression from colon adenoma to cancer. [PDF]

Mol Med
Danesova N, Horak J, Valickova A, Gil-Korilis A, Ergui-Arbizu J, Palek R, Bruha J, Levy M, Skrobanek P, Kral J, Jungwirth J, Neuzil J, Vymetalkova V, Vodicka P, Vodenkova S, Tomasova K.   +15 more
europepmc   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Enhancing cancer susceptibility to disulfidptosis by inducing cell cycle arrest and impairing DNA repair. [PDF]

Theranostics
Lin J, Yang X, Jiang C, Liu X, Shi J.
europepmc   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source

Recombination junctions from antibody isotype switching classify immune and DNA repair dysfunction. [PDF]

Nat Commun
Vázquez García C, Obermayer B, Keller B, Lebedin M, Ratswohl C, Abolhassani H, Busse A, Di Virgilio M, Mathas S, Speiser D, Beule D, Pan-Hammarström Q, Warnatz K, de la Rosa K.   +13 more
europepmc   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

Arthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J. Braaten, Gary A. Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease

McHugh P, Roddan R, Schaich M, Nathan W, Kis I, Pierangelini A, Henderson L, Wee Rv, Martin L, El-Sagheer A, Kukura P, Brown T, O’Brien D, Newman J, iii DW, Schofield C, Houten B.   +16 more
europepmc   +1 more source

The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ. [PDF]

Nat Commun
Martin PR, Nieminuszczy J, Kozik Z, Jakub N, Kowalski S, Lecot M, Vorhauser J, Lane KA, Kanellou A, Mansfeld J, Pearl LH, Oliver AW, Downs JA, Choudhary JS, Day M, Niedzwiedz W.   +15 more
europepmc   +1 more source