Results 211 to 220 of about 1,028,456 (338)

Evidence for improved DNA repair in the long-lived bowhead whale. [PDF]

Nature
Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, Zhang Z, Heid J, Maslov AY, Sun S, Wu Z, Gigas J, Hillpot EC, Martinez JC, Lee M, Williams A, Gilman A, Hamilton N, Strelkova E, Haseljic E, Patel A, Straight ME, Miller N, Ablaeva J, Tam LM, Couderc C, Hoopmann MR, Moritz RL, Fujii S, Pelletier A, Hayman DJ, Liu H, Cai Y, Leung AKL, Zhang Z, Nelson CB, Abegglen LM, Schiffman JD, Gladyshev VN, Maley CC, Modesti M, Genovese G, Simons MJP, Vijg J, Seluanov A, Gorbunova V.   +54 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AMPK phosphorylates WIP1 to promote DNA repair and radioresistance in cancer cells. [PDF]

Cell Death Dis
Lu M, Dong X, Wu C, Wang G, Wang H, Pan Y, Qin Y, Song Y, Pan H, Liu S, Zhang K, Zhang X, Qu J, Yang Z.   +13 more
europepmc   +1 more source

Late Activation of Stress Kinases (SAPK/JNK) by Genotoxins Requires the DNA Repair Proteins DNA-PK_csand CSB

, 2005
Gerhard Fritz, Bernd Kaina
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

LMNA-PRKDC axis enhances DNA repair and promotes chemoresistance in glioblastoma. [PDF]

Cell Death Dis
Saathoff MR, Chojak R, Chen RX, Kazi HA, Faisal UH, Shireman JM, Drewes N, Park CH, Fan X, Khan SA, Lazanyi I, Baisiwala S, James CD, Horbinski CM, Ahmed AU.   +14 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Molecular basis of XPF-ERCC1 targeting to SLX4-dependent DNA repair pathways. [PDF]

Nat Commun
Feng J, Martin PR, Kowalski S, Lecot M, Cronin NB, Matthews-Palmer T, Niedzwiedz W, Greber BJ.   +7 more
europepmc   +1 more source

How Acts of Infidelity Promote DNA Break Repair: Collision and Collusion Between DNA Repair and Transcription

, 2018
Priya Sivaramakrishnan, Alasdair J.E. Gordon, Jennifer A. Halliday, Christophe Herman   +3 more
openalex   +2 more sources

Chromosome fragmentation resulting from an inability to repair transposase-induced DNA double-strand breaks in PCNA mutants of Drosophila [PDF]

, 1998
Daryl S. Henderson, David M. Glover
openalex   +1 more source