Results 211 to 220 of about 3,766,607 (390)
Repair of DNA studied with a nuclease specific for UV-induced lesions.
, 1966 Bernard S. Strauss +2 more
openalex +1 more source
The distribution of DNA repair synthesis in chromatin and its rearrangement following damage with N-acetoxy-2-acetylaminofluorene [PDF]
, 1978 Thea D. Tisty, Michael W. Lieberman
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The influence of chromatin structure on the distribution of DNA repair synthesis studied by nuclease digestion [PDF]
, 1979 William J. Bodell, Mihir R. Banerjee
openalex +1 more source
Mechanisms of DNA damage, repair, and mutagenesis
Environmental and Molecular Mutagenesis, 2017 Nimrat Chatterjee, G. Walker
semanticscholar +1 more source
Neuronal enhancers are hotspots for DNA single-strand break repair
Nature, 2020 Wei Wu +24 more
semanticscholar +1 more source